Results 101 to 110 of about 183,103 (313)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Assessing Coordination of Organic π-Acceptors to Alkali-Metal Nickelates

CHIMIA
Nickel olefin complexes have served as ubiquitous precursors in nickel chemistry ever since their discovery. One class of compounds derived from these precursors is low valent nickelate complexes.
Luca Vedani, Eva Hevia
doaj   +1 more source

Síntese, caracterização e ensaios cinéticos de novos complexos com os ligantes TPEN e Htmdp [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2012A presença de íons metálicos como constituintes naturais das enzimas responsáveis por ...
Coelho, Sara Eulália
core  

When two are better than one: bright phosphorescence from non-stereogenic dinuclear iridium(iii) complexes

, 2016
A new family of eight dinuclear iridium(III) complexes has been prepared, featuring 4,6-diarylpyrimidines Ly as bis-N^C-coordinating bridging ligands. The metal ions are also coordinated by a terminal N^C^N-cyclometallating ligand LX based on 1,3-di(2 ...
Kozhevnikov, V.N., Clegg, William, Hunter, M., Williams, J.A.G., Kozhevnikov, Valery, Daniels, R.E., Clegg, W., Culham, Stacey, Culham, S., Probert, Michael, Probert, M.R., Durrant, Marcus, Daniels, Ruth, Hunter, Michael, Williams, Gareth, Durrant, M.C.   +15 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Computer-aided drug design of photoactivated platinum anticancer complexes [PDF]

Platinum(IV) complexes are usually inert and stable compounds which can be photoactive pro-drugs to produce Pt(II) species with promising anti-cancer activity.
Tai, Hui-Chung
core  

Luminescent lanthanide complexes for cellular applications [PDF]

, 2006
The tetraazatriphenylene chromophore, dpqC, efficiently sensitises europium(III) and terbiiim(lll) emission. It has been incorporated into a series of ligands, based on the :yclen macrocycle, which saturate the coordination sphere of the metal ion and ...
Poole, Robert
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Synthetic, Spectral and Thermal Studies of Tin(IV) Complexes of 1, 5-Benzodiazepines

E-Journal of Chemistry, 2008
Tin(IV) complexes of 7-substituted 6,7-benzo-1,5-dizepines have been synthesized in absolute alcoholic medium. Elemental analysis indicates that the complexes have 1:2 stoichiometry of the type L2SnCl4, TGA data support this conclusion. Molar conductance
Suresh, Padaki Srinivas, T. Suresh, M. Revanasiddappa, Syed Khasim   +4 more
doaj   +1 more source

COORDINATION STATE AND AGGREGATION PROCESS OF BACTERIOCHLOROPHYLL A AND ITS DERIVATIVES : STUDY ON ACETONE-WATER AND METHANOL-WATER SOLVENTS

Indonesian Journal of Chemistry, 2010
Research on bacteriochlorophyll (BChl) a and its derivatives had been conducted to determine the coordination state and the aggregation process in acetone-water and methanol-water.
Heriyanto Heriyanto, Suryasatriya Trihandaru, Leenawaty Limantara   +2 more
doaj   +1 more source