Results 81 to 90 of about 128,402 (265)

Overview of Some Second- and Third-Row Late Transition Metal Pincer-Type N-Heterocyclic Carbene Complexes: Synthesis, Optical Properties, and Applications

Molecules
N-heterocyclic carbenes (NHCs) were first isolated as stable species by Arduengo in 1991. Since then, they have expanded the boundaries of carbene chemistry and sparked extensive research.
Dong-Ling Kuang, Ka-Kit Li, Lai-Hon Chung, Jun He, Chun-Yuen Wong   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Synthesis and characterization of some metal complexes of tetracycline, theophylline and cimetidine

Discover Chemistry
Metal complexes of tetracycline, cimetidine, theophylline, 1, 10-phenanthroline, 2, 2-bipyridine, and imidazole were synthesized via direct reaction of the respective ligands with selected metal salts, namely copper(I) bromide, cobalt carbonate, and ...
Tunde Samuel Adewale, Olufunso O. Abosede   +1 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Copper(II) complexes with 1-methyltetrazole: new method for synthesis and properties

Журнал Белорусского государственного университета: Химия, 2017
A new approach for synthesis of copper(II) complexes with 1-methyltetrazole based on oxidative dissolution of metallic powdercopper in ethanol – HCl (ammonium thiocyanate) was developed. Composition and structure of the complexes prepared were studied by
Andrey N. Bogatikov, Mikhail M. Degtyarik, Oleg A. Ivashkevich   +2 more
doaj  

How vanadium and manganese compounds impact cardiac mitochondrial function

Frontiers in Chemical Biology
IntroductionVanadium and manganese are two biologically relevant redox-active first row transition metals. Both metals have been associated with protective and deleterious effects in the cardiovascular system depending on the biological context, chemical
Connor C. Dolan, Luke A. Whitcomb, Edgar Del Carpio, Edgar Del Carpio, Lilliana Rose, Adam J. Chicco, Debbie C. Crans, Debbie C. Crans   +7 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Unveiling Electrochemical Frontiers: Enhanced Hydrazine Sensing with Na₃[Fe(CN)₅(PZT)] Modified Electrodes

Inorganics
This study presents the synthesis, electrochemical characterization, and sensor application of Na3[Fe(CN)5(PZT)], a novel pentacyanidoferrate-based coordination compound incorporating 2-pyrazinylethanethiol (PZT) as a ligand. Unlike conventional Prussian
Kalil Cristhian Figueiredo Toledo, Juliano Alves Bonacin   +1 more
doaj   +1 more source