Results 41 to 50 of about 1,639,412 (255)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Coordination polymer-forming liquid Cu(2-isopropylimidazolate) [PDF]

open access: yes, 2022
The structure of the melt state of one-dimensional (1D) coordination polymer crystal Cu(isopropylimidazolate) (melting temperature Tm = 143 °C) was characterized by DSC, variable temperature PXRD, solid-state NMR (SSNMR), viscoelastic measurements, XAS ...
Ogawa, Tomohiro   +10 more
core   +1 more source

Ambient blade-coated perovskite solar cells with high reverse bias stability enabled by polymeric hole transporter design

open access: yesNature Communications
Reverse bias stability remains a critical challenge for inverted perovskite solar cells (PSCs). While self-assembled monolayers (SAMs) boost efficiency, their low breakdown voltages limit device reliability.
Chaoyue Zhao   +12 more
doaj   +1 more source

2D Coordination Polymer [Fe(piv)2(dab)2]n

open access: yesMolbank
The interaction of preorganized iron(II) pivalate complexes with aromatic N-donor ligand (pyridine (py) or 2,2′-bipyridine (bpy)) and 1,4-diaminobutane (dab, putrescine) in anhydrous acetonitrile yielded a new 2D coordination polymer [Fe(piv)2(dab)2]n (1,
Vladimir A. Bushuev   +4 more
doaj   +1 more source

Plastic bending in a semiconducting coordination polymer crystal enabled by delamination

open access: yesNature Communications, 2022
Coordination polymers are normally considered to be brittle due to the dominance of directional coordination bonding. Here the authors report the plastic bending in a semiconducting coordination polymer crystal enabled by delamination.
Lian-Cai An   +15 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Thinner-than-paper and broad-temperature-adaptive zinc-iodine batteries enabled by nanophase separated deep-eutectic hydrogel electrolytes

open access: yesNature Communications
Hydrogel electrolyte based secondary batteries are promising for wearable electronics, yet face challenges including limited mechanical resilience, and narrow temperature range. Herein, we report a robust deep-eutectic hydrogel electrolyte fabricated via
Tianyu Shen   +12 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Poly[[bis[μ4-3-(2-carboxylatophenyl)propionato]{N-[2-(pyridine-3-amido)ethyl]nicotinamide}dicopper(II)] pentahydrate]

open access: yesIUCrData, 2023
In the title compound, {[Cu2(C10H8O4)2(C14H14N4O2)]·5H2O}n, the CuII cations are coordinated in a square-pyramidal fashion, with four 3-(2-carboxyphenyl)propionate (cpp) carboxylate O-atom donors in the basal plane, along with an N-atom donor from a N-[2-
Gabrielle J. Gaskin, Robert L. LaDuca
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

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