Results 61 to 70 of about 9,655 (274)

Indocyanine Green Clearance Correlates With Biomarkers Reflecting Key Disease‐Driving Mechanisms in Advanced Chronic Liver Disease and Predicts Acute‐on‐Chronic Liver Failure and Death

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Indocyanine green clearance by pulse dye densitometry correlates with portal hypertension, systemic inflammation and circulatory dysfunction in advanced chronic liver disease. While diagnostic accuracy for CSPH was limited, ICG‐R15 independently predicted decompensation and ACLF/liver‐related mortality, highlighting its prognostic value across disease ...
Mathias Jachs   +17 more
wiley   +1 more source

Evaluation of Copeptin during Pulmonary Exacerbation in Cystic Fibrosis

open access: yesMediators of Inflammation, 2019
Copeptin was found to be a stable biomarker of inflammation and stress response in cardiac, renal, metabolic, and respiratory conditions such as pneumonia.
I. Wojsyk-Banaszak   +8 more
doaj   +1 more source

Effects of sotagliflozin on markers of volume status and sodium handling in patients with type 1 diabetes: A biomarker analysis of the inTandem3 clinical trial

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Sotagliflozin, an inhibitor of sodium‐glucose co‐transporter (SGLT)‐1 and 2, reduces albuminuria, slows GFR decline, and may have diuretic and osmoregulatory effects. The effect of sotagliflozin added to insulin was assessed on markers of neurohormone activation and volume homeostasis in patients with type 1 diabetes (T1D).
Massimo Nardone   +6 more
wiley   +1 more source

Copeptin in aneurysmal subarachnoid hemorrhage [PDF]

open access: yesCritical Care, 2012
Copeptin is a peptide derived from pre-provasospression along with arginine vasospressin. In the setting of aneurysmal subarachnoid hemorrhage (SAH), elevated serum copeptin levels correlate with vasospasm, inpatient mortality, mortality at 1 year, and poor functional outcome at 1 year.
openaire   +2 more sources

Performance of Copeptin for Early Diagnosis of Acute Coronary Syndromes: A Systematic Review and Meta-Analysis of 14,139 Patients

open access: yesJournal of Cardiovascular Development and Disease, 2021
Diagnosis of acute coronary syndrome (ACS) based on copeptin level may enable one to confirm or rule-out acute myocardial infarction (AMI) with higher sensitivity and specificity, which may in turn further reduce mortality rate and decrease the economic ...
Lukasz Szarpak   +9 more
doaj   +1 more source

Data from the German Conn's registry and the KORA F4 Survey [PDF]

open access: yes, 2019
Background: High-sensitive C-reactive protein (hsCRP) and copeptin are new biomarkers that have been shown to be associated with increased morbidity and mortality in patients with cardiovascular and cerebrovascular diseases as well as in the general ...
Remde, Hanna
core   +1 more source

Blood flow restriction: The acute effects of body tilting and reduced gravity analogues on limb occlusion pressure

open access: yesExperimental Physiology, EarlyView.
Abstract Blood flow restriction (BFR) has been identified as a potential countermeasure to mitigate physiological deconditioning during spaceflight. Guidelines recommend that tourniquet pressure be prescribed relative to limb occlusion pressure (LOP); however, it is unclear whether body tilting or reduced gravity analogues influence LOP.
Patrick Swain, Nick Caplan, Luke Hughes
wiley   +1 more source

The stress hormone copeptin: a new prognostic biomarker in acute illness

open access: yesSwiss Medical Weekly, 2010
Stress is defined as anything that throws the body out of homeostatic balance; for example an acute illness. Any stressor which activates the hypothalamo-pituitary-adrenal (HPA) axis leads to an increase in concentrations of the adrenal stress hormone,
M Christ-Crain
doaj   +1 more source

Investigation of possible underlying mechanisms behind water-induced glucose reduction in adults with high copeptin

open access: yesScientific Reports, 2021
Elevated copeptin, a surrogate marker of vasopressin, is linked to low water intake and increased diabetes risk. Water supplementation in habitual low-drinkers with high copeptin significantly lowers both fasting plasma (fp) copeptin and glucose.
Sofia Enhörning   +4 more
doaj   +1 more source

Early diagnosis of acute coronary syndrome. [PDF]

open access: yes, 2017
The diagnostic evaluation of acute chest pain has been augmented in recent years by advances in the sensitivity and precision of cardiac troponin assays, new biomarkers, improvements in imaging modalities, and release of new clinical decision algorithms.
Achenbach, S   +26 more
core   +1 more source

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