Results 101 to 110 of about 25,739 (224)

OMICS Profiling Identifies Signatures of Senescence in Osteogenesis Imperfecta Osteoblasts Counteracted by 4‐PBA

Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Mutations in collagen I are the most common cause of osteogenesis imperfecta (OI), leading to delayed protein folding and structurally abnormal molecules. While some aberrant collagen is secreted into the extracellular matrix (ECM), impairing bone quality, a significant fraction is retained intracellularly, disrupting osteoblast homeostasis. 4‐
Roberta Besio, Elisa Maffioli, Erika Palladino, Alessandra Sala, Nadia Garibaldi, Valerio Izzi, Antonella Forlino, Gabriella Tedeschi   +7 more
wiley   +1 more source

Structural Disorder Provides Increased Adaptability for Vesicle Trafficking Pathways [PDF]

, 2013
Vesicle trafficking systems play essential roles in the communication between the organelles of eukaryotic cells and also between cells and their environment.
A Fotin, A Fotin, A Pagano, A Reider, A Spang, A Wesp, AC Baines, B Eisenhaber, B Meszaros, B Wendland, BA Shoemaker, BG Yeung, BM Collins, C Brocker, C Gurkan, C Kalthoff, C Lee, CG Giraudo, CJ Brown, CL Allen, D Berdnik, D Kummel, D Szklarczyk, DA Shaywitz, E Schad, E ter Haar, EC Dell'Angelica, EC Dimmer, ET Wang, G Ostlund, GS Payne, H Cai, H Folsch, H Hegyi, H Xie, HJ Dyson, HM Ngo, HT McMahon, I von Ossowski, J Bethune, J Malsam, J Moelleken, J Ren, JD Wilbur, JE Gerst, JL Sussman, JR Schaub, K Sato, LM Iakoucheva, Luhua Lai, M Buljan, M Fuxreiter, M Gonzalez-Gaitan, M Punta, MS Robinson, Natalia Pietrosemoli, ND Dwyer, NE Davey, P Flicek, P Tompa, P Tompa, P Tompa, PE Wright, Peter Tompa, PR Evans, R Beck, R Jahn, R Pancsa, R Pancsa, R Sannerud, Rita Pancsa, RJ Weatheritt, RJ Weatheritt, S Fath, SJ Royle, SM Stagg, SM Stagg, SM Stagg, T Kirchhausen, TC Sudhof, TJ Brett, TM Newpher, TR Dafforn, U Consortium, U Scheele, V Legendre-Guillemin, VN Murthy, VW Hsu, W Li, X Chen, Y Lefkir, Y Zhuo, Z Dosztanyi, Z Dosztanyi, Z Dosztanyi   +94 more
core   +3 more sources

PARTICULARITĂȚILE SINDROMULUI METABOLIC LA COPII

Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale, 2022
Prevalența sindromului metabolic la copii este în creștere, în paralel cu tendințele în creștere ale ratelor de obezitate. Diferitele definiții ale acestui sindrom au împiedicat dezvoltarea unui consens pentru criteriile de diagnostic la populația pediatrică, în timp ce patogeneza sindromului metabolic nu este complet înțeleasă.
Cojocari, S.V., Mătrăgună, N.G.
openaire   +2 more sources

Plasmodesmata‐located proteins: The molecular hubs in noncell‐autonomous immunity

New Plant Protection, Volume 3, Issue 1, March 2026.
Plasmodesmata serve as critical battlefields for plant immunity, regulated by diverse proteins. This article provides a comprehensive review of the regulatory mechanisms, challenges, and future directions concerning proteins located within plasmodesmata and their roles in plant defense responses.
Zheng Wu, Xiaoyi Shan
wiley   +1 more source

A novel platform for the production of nonhydroxylated gelatins based on the methylotrophic yeast Hansenula polymorpha [PDF]

, 2007
The use of yeast as a host for heterologous expression of proteins that are normally derived from animal tissue is a promising way to ensure defined products that are devoid of potential harmful animal side products.
Boer, Arjo L. de,, Geerlings, Torsten H.,, Klei, Ida J. van der,, Lunenborg, Marcel G.J.,, Veenhuis, Marten,   +4 more
core   +2 more sources

The Golgi apparatus: 100 years of progress and controversy. [PDF]

, 1998
Research on the Golgi apparatus has resulted in major advances in understanding its structure and functions, but many important questions remain unanswered.
Farquhar, MG, Palade, GE
core  

The endoplasmic reticulum in mitochondrial protein targeting: A neuronal perspective on organelle crosstalk

Protein Science, Volume 35, Issue 3, March 2026.
Abstract Neurons depend on tightly regulated spatial proteostasis to maintain function across their extended morphology. The endoplasmic reticulum (ER), traditionally known for its function in protein synthesis, folding, and trafficking, has long been recognized as a central platform for directing proteins to organelles of the secretory and endocytic ...
J. Tabitha Hees, Angelika B. Harbauer
wiley   +1 more source

Membrane-coating lattice scaffolds in the nuclear pore and vesicle coats: Commonalities, differences, challenges [PDF]

, 2011
The nuclear pore complex (NPC) regulates all traffic between the cytoplasm and the nucleus. It is a large protein assembly composed of multiple copies of ~30 nucleoporins (nups).
Leksa, Nina Carolina, Schwartz, Thomas
core   +1 more source

Particularitățile adenomului și cancerului folicular al glandei tiroide la copii

Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale, 2019
Au fost cercetate – particularitățile adenomului și cancerului folicular al glandei tiroide la copii în perioada anilor 2002-2018. Au fost supuși tratamentului chirurgical 31 de copii cu cancer folicular al glandei tiroide și 42 copii cu adenom folicular.
Andrei Ţîbîrnă, Gheorghe Ţîbîrnă, Silvia Railean, Aurelia Spinei, G. Guțul   +4 more
doaj  

Hijack it, change it: how do plant viruses utilize the host secretory pathway for efficient viral replication and spread? [PDF]

, 2013
The secretory pathway of eukaryotic cells has an elaborated set of endomembrane compartments involved in the synthesis, modification, and sorting of proteins and lipids.
Camilo Patarroyo, Huanquan Zheng, Jean-François Laliberté   +2 more
core   +2 more sources