Results 81 to 90 of about 15,782 (206)
Assembly, organization, and function of the COPII coat [PDF]
Histochemistry and Cell Biology, 2007 A full mechanistic understanding of how secretory cargo proteins are exported from the endoplasmic reticulum for passage through the early secretory pathway is essential for us to comprehend how cells are organized, maintain compartment identity, as well as how they selectively secrete proteins and other macromolecules to the extracellular space.
Hughes, H, Stephens, DJ
openaire +3 more sources
ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate
eLife, 2017 Native cargo proteins exit the endoplasmic reticulum (ER) in COPII-coated vesicles, whereas resident and misfolded proteins are substantially excluded from vesicles by a retention mechanism that remains unresolved.
Wenfu Ma +2 more
doaj +1 more source
Rabdomiosarcomul alveolar mimând leucemia acută la o adolescentă cu tromboză venoasă profundă – caz clinic [PDF]
Romanian Journal of Pediatrics, 2019 Rabdomiosarcomul este cel mai frecvent tip de sarcom al ţesuturilor moi şi se caracterizează prin invadarea şi distrugerea rapidă a ţesuturilor din vecinătate, tendinţa la metastazare fiind mare.
Daniela Vodă +3 more
doaj +1 more source
Advanced Science, Volume 13, Issue 54, 28 September 2026.LRRC4 suppresses GBM by regulating AP2A1‐containing Golgi‐derived clathrin‐coated vesicles. Low LRRC4 allows cytoplasmic AP2A1 to maintain mitochondrial fission‐fusion, MICOS integrity, and OXPHOS, promoting proliferation and invasion. High LRRC4 redirects AP2A1‐containing Golgi‐derived clathrin‐coated vesicles to mitochondria, disrupts MICOS, enhances
Yang Li +5 more
wiley +1 more source
TUMORI ADRENOTESTICULARE LA UN ADOLESCENT CU SINDROM ADRENOGENITAL – REZULTATE DUPĂ UN AN [PDF]
Romanian Journal of Pediatrics, 2012 Introducere. Sindromul adrenogenital este o boală genetică care are ca rezultat producţia scăzută de cortizol şi aldosteron. Pacienţii de sex masculin cu sindrom adrenogenital pot prezenta tumori adrenotesticulare. Scop.
Adela Chiriţă +6 more
doaj +1 more source
Managementul copiilor cu tumori intracerebrale
Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale, 2021 Fundal: Tumorile intracerebrale – reprezintă o nosologie gravă, cu incidență înaltă în rândul copiilor și, deseori, clinica este determinată de apariția hidrocefaliei, cu stoparea pasajului lichidului cefalorahidian de la nivelul formării acestuia până ...
Angela Leancă
doaj +1 more source
Noncoding RNA Transcripts Based Molecular Phenotyping of MASLD and MASH Patients
Liver International Communications, Volume 7, Issue 3, September 2026.ABSTRACT Background and Aims Metabolic dysfunction‐associated steatotic liver disease (MASLD) is a progressive hepatic metabolic disorder characterized by excessive fat accumulation in hepatocytes. MASLD can advance to metabolic dysfunction‐associated steatohepatitis (MASH).
Frida M. Delgadillo +7 more
wiley +1 more source
COPII vesicles and the expansion of the phagophore
eLife, 2019 A new study has identified the proteins that adapt COPII vesicles to the needs of starving cells.
openaire +5 more sources
EVALUARE EPIDEMIOLOGICĂ ŞI PSIHO-SOCIALĂ A COPILULUI OBEZ – STUDIU PROSPECTIV [PDF]
Romanian Journal of Pediatrics, 2016 Obiectiv. Studiul de faţă şi-a propus evaluarea unor parametri epidemiologici şi psiho-sociali într-un eşantion de copii supraponderali şi obezi spitalizaţi pentru diverse patologii. Durata studiului a fost de 12 luni. Material şi metodă.
Oana Elena Iaru +6 more
doaj +1 more source
MedComm – Oncology, Volume 5, Issue 3, September 2026.The up‐to‐date clinical progress of immune checkpoint inhibitor (ICI) therapy in solid tumors, specifically the combinational regimens between ICIs and other treatment strategies, the mechanisms underlying primary and acquired resistance, and mechanism‐matched strategies to improve clinical outcomes are synthesized in this review.
Qiongyu Zhang, Zhi Qin, Caijuan Guo
wiley +1 more source