Results 91 to 100 of about 25,739 (224)

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, Volume 14, Issue 4, Page 978-991, May 2026.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

Protein trafficking through the endosomal system prepares intracellular parasites for a home invasion [PDF]

, 2013
Toxoplasma (toxoplasmosis) and Plasmodium (malaria) use unique secretory organelles for migration, cell invasion, manipulation of host cell functions, and cell egress. In particular, the apical secretory micronemes and rhoptries of apicomplexan parasites
A Fomovska, AE Topolska, B Lige, B Shen, BF Kafsack, BJ Luft, C Lord, CA Hunter, Chetan E. Chitnis, Christian Slomianny, CY He, D Richard, DL Alexander, F Parussini, H El Hajj, HC Hoppe, HC Hoppe, I Mellman, J Schrevel, JB Dacks, JC Boothroyd, JE Rothman, JF Dubremetz, JM Harper, K Kremer, K Miranda, KA Joiner, KA Joiner, KM Hager, L Pelletier, L Sheiner, LH Bannister, LH Bannister, LM Kats, M Elias, M Tufet-Bayona, M Yang, Markus Meissner, ME Francia, MH Ngo, MH Ngo, MK Shaw, MS Breinich, MS Marks, NA Counihan, PJ Bradley, PJ Sloves, S Mogelsvang, SD Brydges, Stanislas Tomavo, VB Carruthers, Vern B. Carruthers, WM Henne, X Que, Z Dou   +54 more
core   +2 more sources

The Critical Role of GALNTs‐Regulated O‐GalNAc Glycosylation in Cancer Malignancy

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
The GALNT family initiates mucin‐type O‐GalNAc glycosylation in the Golgi apparatus and how regulatory mechanisms, including GALNT relocalization and microRNA control, modulate this process. Dysregulated O‐GalNAc glycosylation alters key cellular behaviors and promotes cancer malignancy, highlighting its relevance to tumor progression as well as its ...
Jiahao Liu, Sihan Wu, Ge Zhang, Jiehan Li, Yuhan Yin, Aman Uiiah, Sanfei Peng, Yang Fu   +7 more
wiley   +1 more source

Cholesterol impairment contributes to neuroserpin aggregation [PDF]

, 2017
Intraneural accumulation of misfolded proteins is a common feature of several neurodegenerative pathologies including Alzheimer's and Parkinson's diseases, and Familial Encephalopathy with Neuroserpin Inclusion Bodies (FENIB). FENIB is a rare disease due
Costantini, Giulio, Giampietro, Costanza, La Porta, Caterina A. M., Lionetti, Maria Chiara, Mutti, Federico, Zapperi, Stefano   +5 more
core   +2 more sources

SISTEMUL DE CLASIFICARE A FUNCŢIEI MOTORII GROSIERE ŞI SISTEMUL DE CLASIFICARE A ABILITĂŢII MANUALE ÎN EVALUAREA PARALIZIEI CEREBRALE [PDF]

Romanian Journal of Pediatrics, 2016
Paralizia cerebrală (PC) este o boală cerebrală cronică, definită ca un grup de afecţiuni motorii neprogresive care debutează în primul an de viaţă şi care sunt secundare leziunilor survenite la un creier aflat în dezvoltare.
Ioana Grigore, Georgeta Diaconu, Cătălin Prazaru, Alexandra Mania, Ana Ulinici   +4 more
doaj   +1 more source

An engineered epididymal cell line provides a sustainable source of functional extracellular vesicles for in vitro sperm preservation: A multi‐omics and functional study

VIEW, Volume 7, Issue 2, April 2026.
Schematic representation of the contribution of EVs proteins secreted by successfully established pEECs to sperm. pEECs‐derived EVs support sperm preservation in vitro through improved antioxidant capacity and viability, accompanied by reduced oxidative damage to membranes, mitochondria, DNA integrity and cell death.
Long Li, Haonan Zhao, Yibo Li, Qixin Xu, Yang Zi, Tingting Chu, Heran Cao, Shujuan Liu, Zifang Wu, Huanqiang Zhao, Wuzi Dong   +10 more
wiley   +1 more source

A Role for Actin, Cdc1p, and Myo2p in the Inheritance of Late Golgi Elements in \u3cem\u3eSaccharomyces cerevisiae\u3c/em\u3e [PDF]

, 2001
In Saccharomyces cerevisiae, Golgi elements are present in the bud very early in the cell cycle. We have analyzed this Golgi inheritance process using fluorescence microscopy and genetics.
Bevis, Brooke J., Glick, Benjamin S., Hammond, Adam T., O\u27Connor, James, Reinke, Catherine A., Rossanese, Olivia W., Sears, Irina B.   +6 more
core   +1 more source

COPILUL CU AFECŢIUNI ONCOLOGICE ÎN TERAPIA INTENSIVĂ [PDF]

Romanian Journal of Pediatrics, 2012
Progresele făcute în oncologie în decursul ultimilor ani au ameliorat considerabil prognosticul copiilor cu afecţiuni neoplazice. Ameliorarea supravieţuirii se însoţeşte însă de o creştere a riscului de complicaţii severe pentru care pacientul poate ...
N. Nistor, Georgiana Russu, Ingrith Miron, Irina-Mihaela Ciomaga, Cristina Jităreanu, Violeta Ştreangă   +5 more
doaj   +1 more source

When Aid Comes With Strings: Donor Power and Everyday Anti‐Trafficking Work in Moldova

International Migration, Volume 64, Issue 2, April 2026.
ABSTRACT Anti‐trafficking governance in Moldova unfolds far from the conference rooms where global priorities are set. Drawing on ethnographically informed research and 15 interviews with frontline practitioners, this article shows how donor agendas shape the daily realities of anti‐trafficking work, not only through funding, but through the softer ...
Ludmila Bogdan
wiley   +1 more source

Easter Celebration [PDF]

, 2015
Easter is the most important solemnity (just before Christmas) of the Church. It is the first of the five cardinal feasts of the Catholic liturgical year.
Sfetcu, Nicolae
core