Results 71 to 80 of about 25,739 (224)

Biogenesis of TNF‐α‐insights into proteostasis and inflammation

The FEBS Journal, EarlyView.
TNF‐α biogenesis, trafficking, and signalling are tightly and reciprocally coupled to cellular proteostasis systems, including ER chaperones and endoplasmic reticulum‐associated degradation. This bidirectional crosstalk determines whether TNF‐α responses are adaptive or proteotoxic.
Bailasan Haidar, Céline Philippe, Eric Chevet, Jiří Zahradník   +3 more
wiley   +1 more source

Cauzele genetice asociate accidentului vascular cerebral ischemic la copii.

Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale, 2020
Introducere. Accidentul vascular cerebral ischemic (AVCI) reprezintă o boală rară la copii și adolescenți, deseori subestimată, cu un impact major asupra morbidității și mortalității.
Mariana Sprincean, Svetlana Hadjiu, Cornelia Călcîi, Elena Halabudenco, Nadejda Lupuşor, Ninel Revenco, Stanislav Groppa   +6 more
doaj  

Pancreatic beta cell ER export in health and diabetes

Frontiers in Endocrinology, 2023
In the secretory pathway of the pancreatic beta cell, proinsulin and other secretory granule proteins are first produced in the endoplasmic reticulum (ER). Beta cell ER homeostasis is vital for normal beta cell functions and is maintained by the delicate
Cesar Barrabi, Kezhong Zhang, Ming Liu, Xuequn Chen   +3 more
doaj   +1 more source

SIB1‐SEC23A undergo ER to chloroplast relocalization to mediate immunity in Arabidopsis thaliana

Journal of Integrative Plant Biology, EarlyView.
SEC23A mediates membrane trafficking between the endoplasmic reticulum (ER) and Golgi apparatus and interacts with the immunity protein SIGMA FACTOR‐BINDING PROTEIN1 in Arabidopsis. Under stress, both proteins relocate from the ER to chloroplasts, suppressing photosynthesis genes and enhancing defense genes.
Jialin Peng, Huan Zhong, Jianan Zhang, Hailei Zhang, Wuzhen Liu, Yonglun Zeng, Liwen Jiang, Yiji Xia   +7 more
wiley   +1 more source

An ancestral secretory apparatus in the protozoan parasite Giardia intestinalis [PDF]

, 2003
The protozoan parasite Giardia intestinalis belongs to one of the earliest diverged eukaryotic lineages. This is also reflected in a simple intracellular organization, as Giardia lacks common subcellular compartments such as mitochondria, peroxisomes ...
Hehl, Adrian B., Knopf, Lea G., Li, Yajie, Marti, Matthias, Müller, Norbert, Regös, Attila, Schraner, Elisabeth M., Wild, Peter   +7 more
core   +1 more source

SINDROM ADRENOGENITAL LA NOU-NĂSCUT [PDF]

Romanian Journal of Pediatrics, 2013
Deshidratarea acută severă la sugar poate să survină în contextul unor multiple cauze etiologice, cea mai frecventă fi ind gastroenterita acută. Rezistenţa la tratamentul de corecţie electrolitic şi acidobazic prin persistenţa hiponatremiei alături de ...
Alina Murgu, Cătălina Ionescu, F. Cristogel, Adriana Baltag, Cezarina Dragomirescu, Evelina Moraru   +5 more
doaj   +1 more source

Managementul copiilor cu tumori intracerebrale

Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale, 2021
Fundal: Tumorile intracerebrale – reprezintă o nosologie gravă, cu incidență înaltă în rândul copiilor și, deseori, clinica este determinată de apariția hidrocefaliei, cu stoparea pasajului lichidului cefalorahidian de la nivelul formării acestuia până ...
Angela Leancă
doaj   +1 more source

Unfolding Plant Defence: Endoplasmic Reticulum Stress Signalling at the Plant‐Pathogen Interface

Plant Biotechnology Journal, EarlyView.
ABSTRACT The endoplasmic reticulum (ER) stress response, a conserved proteostasis network, has emerged as a central hub that reprograms plant immunity during pathogen attack. This review synthesises how plants harness ER‐stress signalling to mount multilayered defences and how pathogens have evolved counterstrategies to subvert these pathways.
Zhe Meng, Shuqin Zheng, Federica Brandizzi, Yiran Liu, Chunlei Li, Congcong Ai, Yujiao Wang, Jiadong Qi, Xiuguo Zhang   +8 more
wiley   +1 more source

Rabdomiosarcomul alveolar mimând leucemia acută la o adolescentă cu tromboză venoasă profundă – caz clinic [PDF]

Romanian Journal of Pediatrics, 2019
Rabdomiosarcomul este cel mai frecvent tip de sarcom al ţesuturilor moi şi se caracterizează prin invadarea şi distrugerea rapidă a ţesuturilor din vecinătate, tendinţa la metastazare fiind mare.
Daniela Vodă, Anca Corina Leonte, Carmen Oţelea, Anca Maria Ilea   +3 more
doaj   +1 more source

The Lack of a COPII Cargo Receptor Erv14 Impacts Physiological Functions of the Vacuole in Saccharomyces cerevisiae

Traffic, Volume 27, Issue 2, June 2026.
Loss of the cargo receptor Erv14 in Saccharomyces cerevisiae results in sensitivity to calcium, zinc, neutral extracellular pH, and elevated temperature. Furthermore, cells deleted in the ERV14 exhibits vacuolar fragmentation, enlarged lipid droplets, and metabolic alterations. Ruiz Salas, J. L. (2026) https://BioRender.com/b65g523. ABSTRACT Erv14 is a
Paul Rosas‐Santiago, Jorge Luis Ruiz Salas, Elizabeth Cordoba, Francisco Vera‐López Portillo, Prisciluis Caheri Salas‐Navarrete, Jaime Arturo Pimentel Cabrera, Alfredo Martínez, Nayeli Imelda Roldan Ramírez, Dieter Chavelas Hernández, Andrés Saralegui‐Amaro, Martha Calahorra, Hana Sychrová, Olga Zimmermannová   +12 more
wiley   +1 more source