Results 61 to 70 of about 8,702 (177)
Managementul copiilor cu tumori intracerebrale
Fundal: Tumorile intracerebrale – reprezintă o nosologie gravă, cu incidență înaltă în rândul copiilor și, deseori, clinica este determinată de apariția hidrocefaliei, cu stoparea pasajului lichidului cefalorahidian de la nivelul formării acestuia până ...
Angela Leancă
doaj +1 more source
ABSTRACT Rice has developed an efficient system for manganese (Mn) uptake, mediated by two distinct transporters, OsNramp5 and OsMTP9. These transporters exhibit polar localization at the root exodermis and endodermis; however, the mechanisms underlying their polar localization and their role in Mn uptake remain unclear.
Noriyuki Konishi, Jian Feng Ma
wiley +1 more source
SINDROM ADRENOGENITAL LA NOU-NĂSCUT [PDF]
Deshidratarea acută severă la sugar poate să survină în contextul unor multiple cauze etiologice, cea mai frecventă fi ind gastroenterita acută. Rezistenţa la tratamentul de corecţie electrolitic şi acidobazic prin persistenţa hiponatremiei alături de ...
Alina Murgu +5 more
doaj +1 more source
Pancreatic beta cell ER export in health and diabetes
In the secretory pathway of the pancreatic beta cell, proinsulin and other secretory granule proteins are first produced in the endoplasmic reticulum (ER). Beta cell ER homeostasis is vital for normal beta cell functions and is maintained by the delicate
Cesar Barrabi +3 more
doaj +1 more source
Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song +6 more
wiley +1 more source
Rabdomiosarcomul alveolar mimând leucemia acută la o adolescentă cu tromboză venoasă profundă – caz clinic [PDF]
Rabdomiosarcomul este cel mai frecvent tip de sarcom al ţesuturilor moi şi se caracterizează prin invadarea şi distrugerea rapidă a ţesuturilor din vecinătate, tendinţa la metastazare fiind mare.
Daniela Vodă +3 more
doaj +1 more source
From EM to AI: Multiscale imaging of the secretory pathway with insights from plant cells
Abstract The secretory pathway is a central and evolutionarily conserved feature of eukaryotic cells, responsible for protein and lipid trafficking, membrane biogenesis, signalling, and cellular homeostasis. Its complexity, dynamic behaviour, and nanoscale organisation have made it a longstanding target of microscopy‐driven investigation.
Charlotte Pain, Emily Farley
wiley +1 more source
Assembly, organization, and function of the COPII coat [PDF]
A full mechanistic understanding of how secretory cargo proteins are exported from the endoplasmic reticulum for passage through the early secretory pathway is essential for us to comprehend how cells are organized, maintain compartment identity, as well as how they selectively secrete proteins and other macromolecules to the extracellular space.
Hughes, H, Stephens, DJ
openaire +3 more sources
ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate
Native cargo proteins exit the endoplasmic reticulum (ER) in COPII-coated vesicles, whereas resident and misfolded proteins are substantially excluded from vesicles by a retention mechanism that remains unresolved.
Wenfu Ma +2 more
doaj +1 more source
TUMORI ADRENOTESTICULARE LA UN ADOLESCENT CU SINDROM ADRENOGENITAL – REZULTATE DUPĂ UN AN [PDF]
Introducere. Sindromul adrenogenital este o boală genetică care are ca rezultat producţia scăzută de cortizol şi aldosteron. Pacienţii de sex masculin cu sindrom adrenogenital pot prezenta tumori adrenotesticulare. Scop.
Adela Chiriţă +6 more
doaj +1 more source

