Results 51 to 60 of about 8,702 (177)

COPII and exit from the endoplasmic reticulum

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2005
First discovered by genetic analysis of yeast secretion mutants, the evolutionarily conserved vesicular coat protein II (COPII) complex is responsible for membrane transport from the endoplasmic reticulum (ER) to the Golgi apparatus. In recent years, extensive efforts in structural, morphological, genetic and molecular analysis have greatly enhanced ...
Tang, Bor Luen, Wang, Ya, Ong, Yan Shan, Hong, Wanjin   +3 more
openaire   +2 more sources

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source

INDICELE INTIMĂ MEDIE CAROTIDIAN LA COPIII OBEZI NĂSCUŢI CU GREUTATE MICĂ PENTRU VÂRSTA GESTAŢIONALĂ VERSUS CEI NĂSCUŢI CU GREUTATE NORMALĂ PENTRU VÂRSTA GESTAŢIONALĂ [PDF]

Romanian Journal of Pediatrics, 2014
Indicele intimǎ medie carotidian (IMc) este un cunoscut marker subclinic pentru aterosclerozǎ. Fenomenul de recuperare nutriţionalǎ la copiii nǎscuţi mici pentru vârsta gestaţionalǎ (SGA) a fost asociat cu obezitate precoce şi cu riscul dezvoltǎrii ...
Ramona Stroescu, Ioana Micle, Teofana Bizerea, Monica Mărăzan, Maria Puiu, Gabriela Doroş, Otilia Mărginean   +6 more
doaj   +1 more source

Biogenesis of TNF‐α‐insights into proteostasis and inflammation

The FEBS Journal, EarlyView.
TNF‐α biogenesis, trafficking, and signalling are tightly and reciprocally coupled to cellular proteostasis systems, including ER chaperones and endoplasmic reticulum‐associated degradation. This bidirectional crosstalk determines whether TNF‐α responses are adaptive or proteotoxic.
Bailasan Haidar, Céline Philippe, Eric Chevet, Jiří Zahradník   +3 more
wiley   +1 more source

Phosphorylation of Chs2p regulates interaction with COPII [PDF]

Journal of Cell Science, 2013
Trafficking of the chitin synthase Chs2p from the endoplasmic reticulum (ER) to the bud-neck in late mitosis is tightly regulated by the cell cycle via phosphorylation of serine residues in the N-terminus of the protein. Here, we describe the effects of Chs2p phosphorylation on interaction with coat protein complex II (COPII).
Mia Kyed, Jakobsen, Zhiliang, Cheng, Sheung Kwan, Lam, Elizabeth, Roth-Johnson, Robyn M, Barfield, Randy, Schekman   +5 more
openaire   +2 more sources

SIB1‐SEC23A undergo ER to chloroplast relocalization to mediate immunity in Arabidopsis thaliana

Journal of Integrative Plant Biology, EarlyView.
SEC23A mediates membrane trafficking between the endoplasmic reticulum (ER) and Golgi apparatus and interacts with the immunity protein SIGMA FACTOR‐BINDING PROTEIN1 in Arabidopsis. Under stress, both proteins relocate from the ER to chloroplasts, suppressing photosynthesis genes and enhancing defense genes.
Jialin Peng, Huan Zhong, Jianan Zhang, Hailei Zhang, Wuzhen Liu, Yonglun Zeng, Liwen Jiang, Yiji Xia   +7 more
wiley   +1 more source

SINDROMUL MÜNCHAUSEN PRIN TRANSFER – O PROBLEMĂ REALĂ PEDIATRICĂ? [PDF]

Romanian Journal of Pediatrics, 2015
Sindromul Münchausen (SM) şi Münchausen prin transfer (SMPT) aparţin afecţiunilor numite „Factitious disorder şi reprezintă tulburări mentale severe care au ca „scop“ situaţia de a deveni pacient respectiv de a „fabrica“ o boală unei alte persoane, afl ...
Daniela Păcurar, Maria Runcan, Anca Popescu, Gabriela Leşanu, Dumitru Orăşeanu   +4 more
doaj   +1 more source

Unfolding Plant Defence: Endoplasmic Reticulum Stress Signalling at the Plant‐Pathogen Interface

Plant Biotechnology Journal, EarlyView.
ABSTRACT The endoplasmic reticulum (ER) stress response, a conserved proteostasis network, has emerged as a central hub that reprograms plant immunity during pathogen attack. This review synthesises how plants harness ER‐stress signalling to mount multilayered defences and how pathogens have evolved counterstrategies to subvert these pathways.
Zhe Meng, Shuqin Zheng, Federica Brandizzi, Yiran Liu, Chunlei Li, Congcong Ai, Yujiao Wang, Jiadong Qi, Xiuguo Zhang   +8 more
wiley   +1 more source

A role for Yip1p in COPII vesicle biogenesis [PDF]

The Journal of Cell Biology, 2003
Yeast Ypt1p-interacting protein (Yip1p) belongs to a conserved family of transmembrane proteins that interact with Rab GTPases. We encountered Yip1p as a constituent of ER-derived transport vesicles, leading us to hypothesize a direct role for this protein in transport through the early secretory pathway.
Heidtman, Matthew, Chen, Catherine Z., Collins, Ruth N., Barlowe, Charles   +3 more
openaire   +2 more sources

Cauzele genetice asociate accidentului vascular cerebral ischemic la copii.

Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale, 2020
Introducere. Accidentul vascular cerebral ischemic (AVCI) reprezintă o boală rară la copii și adolescenți, deseori subestimată, cu un impact major asupra morbidității și mortalității.
Mariana Sprincean, Svetlana Hadjiu, Cornelia Călcîi, Elena Halabudenco, Nadejda Lupuşor, Ninel Revenco, Stanislav Groppa   +6 more
doaj