Results 31 to 40 of about 15,782 (206)

Sequence-directed concentration of G protein-coupled receptors in COPII vesicles

iScience, 2023
Summary: G protein-coupled receptors (GPCRs) constitute the largest superfamily of plasma membrane signaling proteins. However, virtually nothing is known about their recruitment to COPII vesicles for forward delivery after synthesis in the endoplasmic ...
Xin Xu, Nevin A. Lambert, Guangyu Wu
doaj   +1 more source

Etica relației dintre copii, părinți și stat [PDF]

, 2021
Care este statutul moral al copiilor? Ce înseamnă egalitatea morală dintre copii şi adulți? Care sunt constrângerile pe care le impune acceptarea acestei egalități în ceea ce priveşte felul în care pot fi tratați copiii în familie sau în societate?
Cutas, Daniela
core   +2 more sources

The Sar1 GTPase coordinates biosynthetic cargo selection with endoplasmic reticulum export site assembly. [PDF]

, 2001
Cargo selection and export from the endoplasmic reticulum is mediated by the COPII coat machinery that includes the small GTPase Sar1 and the Sec23/24 and Sec13/31 complexes.
Bannykh, Sergei, Balch, WE, William E. Balch, Aridor, M, Balch, William E, Fish, KN, Lippincott-Schwartz, J, Fish, Kenneth N, Lippincott-Schwartz, Jennifer, Meir Aridor, Weissman, Jacques, Sergei Bannykh, Jacques Weissman, Bannykh, S, Roberts, Theresa H, Weissman, J, Aridor, Meir, Jennifer Lippincott-Schwartz, Roberts, TH, Theresa H. Roberts, Kenneth N. Fish   +20 more
core   +1 more source

ARF-GAP-mediated interaction between the ER-Golgi v-SNAREs and the COPI coat [PDF]

, 2002
In eukaryotic cells, secretion is achieved by vesicular transport. Fusion of such vesicles with the correct target compartment relies on SNARE proteins on both vesicle (v-SNARE) and the target membranes (t-SNARE).
Rein, U., Rein, Ulrike, Anne Spang, Spang, Anne, Hans Dieter Schmitt, Andag, Uwe, Ulrike Rein, Duden, R., Schmitt, Hans Dieter, Duden, Rainer, Spang, A., Andag, U., Uwe Andag, Schmitt, H. D., Rainer Duden, Schmitt, H.   +15 more
core   +1 more source

ACUTE GASTROENTERITIS IN CHILDREN-THERAPEUTIC PRINCIPLES [PDF]

Romanian Journal of Pediatrics, 2008
This report presents updated recommendations for the optimal management of acute gastroenteritis in childhood, according to fundamental therapeutical principles recommended by ESPGHAN ( European Society of Paediatric Gastroenterology, Hepatology and ...
Victoria Hurduc, Valeriu Popescu, Dimitrie Dragomir, Doina Pleșca, Luiza Preda   +4 more
doaj   +1 more source

PERSPECTIVELE TERAPIEI IMUNOMODULATOARE ÎN ASTMUL PEDIATRIC [PDF]

Romanian Journal of Pediatrics, 2010
Astmul bronşic este un sindrom infl amator al căilor aeriene cu mecanism complex de producere. Studiul patogeniei sale imune a oferit oportunităţi nebănuite noilor terapii imunomodulatoare.
Dimitrie Dragomir, Doina Anca Pleşca, Victoria Hurduc, Felicia Cora, A. Zamfirescu   +4 more
doaj   +1 more source

Surface structure of the COPII-coated vesicle [PDF]

Proceedings of the National Academy of Sciences, 2001
The spatial arrangement of COPII coat protein subunits was analyzed by crosslinking to an artificial membrane surface and by electron microscopy of coat proteins and coated vesicle surfaces. The efficiency of COPII subunit crosslinking to phospholipids declined in order of protein recruitment to the coat: Sar1p > Sec23/24p ≫ Sec13/31p.
K, Matsuoka, R, Schekman, L, Orci, J E, Heuser   +3 more
openaire   +2 more sources

Cell-free Generation of COPII-coated Procollagen I Carriers

Bio-Protocol, 2017
The aim of this protocol is to generate COPII-coated procollagen I (PC1) carriers in a cell-free reaction. The COPII-coated PC1 carriers were reconstituted from donor membrane, cytosol, purified recombinant COPII proteins, and nucleotides.
Lin Yuan, Satoshi Baba, Kanika Bajaj, Randy Schekman   +3 more
doaj   +1 more source

Structural Disorder Provides Increased Adaptability for Vesicle Trafficking Pathways [PDF]

, 2013
Vesicle trafficking systems play essential roles in the communication between the organelles of eukaryotic cells and also between cells and their environment.
Peter Tompa, Rita Pancsa (173029), Natalia Pietrosemoli (280470), Pancsa Rita, Tompa Peter, Peter Tompa (38445), Pietrosemoli Natalia, Tompa, Péter, Rita Pancsa, Pietrosemoli, Natalia, Natalia Pietrosemoli, Pancsa, Rita   +11 more
core   +1 more source

Nutrient deprivation alters the rate of COPII subunit recruitment at ER subdomains to tune secretory protein transport

Nature Communications, 2023
Co-assembly of the multilayered coat protein complex II (COPII) with the Sar1 GTPase at subdomains of the endoplasmic reticulum (ER) enables secretory cargoes to be concentrated efficiently within nascent transport intermediates, which subsequently ...
William Kasberg, Peter Luong, Kevin A. Swift, Anjon Audhya   +3 more
doaj   +1 more source