Results 41 to 50 of about 8,729 (179)
MIDDLE EAR CHOLESTEATOMA OTITIS AFTER GROMMET INSERTION [PDF]
Romanian Medical Journal, 2018 Objective. Presenting a rare case of middle ear cholesteatoma, possible as a result of grommet insertion. The disease occured a few months after tympanostomy tube spontaneous extrusion.
Adina Zamfir-Chiru-Anton +4 more
doaj +1 more source
Tumorile cavităţii bucale la copii. Abordare de diagnostic
Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale, 2021 Tumorile cavității bucale la copii. Abordare de diagnostic. Deși majoritatea leziunilor raportate la copii și adolescenți sunt benigne, ar trebui să se recunoască faptul că tumorile maligne orale apar la copii.
Dănis Ursu +4 more
doaj +1 more source
COPII — a flexible vesicle formation system [PDF]
Current Opinion in Cell Biology, 2013 Long known as a coat system that generates small transport vesicles from the endoplasmic reticulum (ER), the COPII coat also drives ER export of cargo proteins that are too large to be contained within these canonical carriers. With crystal and cryo-EM structures giving an atomic level view of coat architecture, current advances in the field have ...
Elizabeth A, Miller, Randy, Schekman
openaire +2 more sources
PLoS ONE, 2014 The formation and budding of endoplasmic reticulum ER-derived vesicles depends on the COPII coat protein complex that was first identified in yeast Saccharomyces cerevisiae. The ER-associated Sec12 and the Sar1 GTPase initiate the COPII coat formation by
Johan-Owen De Craene +7 more
doaj +1 more source
PSEUDOPUBERTATEA PRECOCE – MANIFESTARE PARANEOPLAZICĂ RARĂ ÎN HEPATOBLASTOM [PDF]
Romanian Journal of Pediatrics, 2011 Hepatoblastomul este cea mai frecventă tumoră malignă hepatică la copil, reprezentând 1-2% din totalul cancerelor copilului. Prognosticul rămâne rezervat la pacienţii cu reziduu tumoral postoperator iniţial chiar în condiţiile chimioterapiei intensifi ...
Ingrid Miron +6 more
doaj +1 more source
Advanced Science, EarlyView.LRRC4 suppresses GBM by regulating AP2A1‐containing Golgi‐derived clathrin‐coated vesicles. Low LRRC4 allows cytoplasmic AP2A1 to maintain mitochondrial fission‐fusion, MICOS integrity, and OXPHOS, promoting proliferation and invasion. High LRRC4 redirects AP2A1‐containing Golgi‐derived clathrin‐coated vesicles to mitochondria, disrupts MICOS, enhances
Yang Li +5 more
wiley +1 more source
COPII and exit from the endoplasmic reticulum
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2005 First discovered by genetic analysis of yeast secretion mutants, the evolutionarily conserved vesicular coat protein II (COPII) complex is responsible for membrane transport from the endoplasmic reticulum (ER) to the Golgi apparatus. In recent years, extensive efforts in structural, morphological, genetic and molecular analysis have greatly enhanced ...
Tang, Bor Luen +3 more
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Viruses, 2023 Porcine epidemic diarrhea virus (PEDV) is an alpha-coronavirus causing acute diarrhea and high mortality in neonatal suckling piglets, resulting in huge economic losses for the global swine industry.
Ying Yang +5 more
doaj +1 more source
Advanced Science, EarlyView.Lactate accumulation in glioblastoma drives lactylation of STING at lysine 370, a primate‐conserved residue. K370 lactylation weakens STING‐TBK1 binding, destabilizes STING, and disrupts ER‐to‐Golgi trafficking, blunting type I interferon signaling. LDHA inhibition reverses K370 lactylation and improves the antitumor efficacy of STING agonism combined ...
Yueyao Wu +11 more
wiley +1 more source
Secretopathies emerge as a new class of neurocristopathies
Developmental Dynamics, EarlyView.Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira +3 more
wiley +1 more source