Results 21 to 30 of about 417,499 (265)
IUBMB Life, 2017 AbstractMetallothioneins (MTs) are a class of low molecular weight and cysteine‐rich metal binding proteins present in all the branches of the tree of life. MTs efficiently bind with high affinity several essential and toxic divalent and monovalent transition metals by forming characteristic polynuclear metal‐thiolate clusters within their structure ...
Jenifer, Calvo +2 more
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The Outlook for Taiwan’s New President, Lai Ching-te
East Asian PolicyOn 13 January 2024, Taiwan elected Lai Ching-te as its new president, marking the first time a single political party won three consecutive times. Despite this victory, the Democratic Progressive Party did not secure a legislative majority, spelling a ...
John F COPPER
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Geosciences, 2012 An extensive late Aeronian patch reef swarm outcrops for 60–70 km on Anticosti Island, eastern Canada, located in the inner to mid-shelf area of a prominent tropical carbonate platform of southeastern Laurentia, at 20°–25° S paleolatitude of the southern
Jisuo Jin, Paul Copper
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A Comparative Study on the Condensation Heat Transfer of R-513A as an Alternative to R-134a
Machines, 2021 This paper presents the two-phase condensation heat transfer and pressure drop characteristics of R-513A as an alternative refrigerant to R-134a in a 9.52-mm OD horizontal microfin copper tube.
Andreas Karageorgis +2 more
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Substantiation of the effective geotechnological parameters of activation heap leaching of gold from refractory ores [PDF]
E3S Web of Conferences, 2020 The difficulties associated with the hydrometallurgical processing of refractory ores and some methods of their solution are discussed in the article. Difficulties associated with leaching of goldcopper ores are characterized.
Rasskazova Anna, Korpi Paul
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Contact Dermatitis, 2014 The world production of copper is steadily increasing. Although humans are widely exposed to copper‐containing items on the skin and mucosa, allergic reactions to copper are only infrequently reported. To review the chemistry, biology and accessible data to clarify the implications of copper hypersensitivity, a database search of PubMed was performed ...
Simon W, Fage +2 more
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
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Frontiers in ChemistryIntroductionWhether in industrial production or daily life, froth plays an important role in many processes. Sometimes, froth exists as a necessity and is also regarded as the typical characteristic of products, e.g., froth on shampoo.
Tiefeng Peng +3 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source