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Expression of copper metabolism-related genes is associated with the tumor immune microenvironment and predicts the prognosis of hepatocellular carcinoma. [PDF]
Transl Cancer ResKong L +7 more
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Aspergillus fumigatus copper export machinery and reactive oxygen intermediate defense counter host copper-mediated oxidative antimicrobial offense [PDF]
, 2017 Dinauer, Mary C, et al,, Idol, Rachel A
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A novel copper metabolism-related signature model for predicting the prognosis, target drugs, and immunotherapy in stomach adenocarcinoma. [PDF]
Genes DisZhuang K +8 more
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New England Journal of Medicine, 1961
THE element copper is ubiquitously distributed on the earth's surface. Its tin alloy, bronze, has been in use for four thousand years, and the salts of the metal were employed in the therapy of eye...
S J, ADELSTEIN, B L, VALLEE
exaly +6 more sources
THE element copper is ubiquitously distributed on the earth's surface. Its tin alloy, bronze, has been in use for four thousand years, and the salts of the metal were employed in the therapy of eye...
S J, ADELSTEIN, B L, VALLEE
exaly +6 more sources
Cellular Copper Transport and Metabolism
Annual Review of Nutrition, 2000The transport and cellular metabolism of Cu depends on a series of membrane proteins and smaller soluble peptides that comprise a functionally integrated system for maintaining cellular Cu homeostasis. Inward transport across the plasma membrane appears to be a function of integral membrane proteins that form the channels that select Cu ions for ...
openaire +4 more sources
Genes regulating copper metabolism
Molecular and Cellular Biochemistry, 1998The metabolism of Cu is intimately linked with its nutrition. From gut to enzymes, Cu bioavailability to key enzymes and other components operates through a complex mechanism that uses transport proteins as well as small molecular weight ligands. Steps in Cu transport through the blood, absorption by cells, and incorporation into enzymes are slowly ...
E D, Harris, Y, Qian, M C, Reddy
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Molecular Aspects of Medicine, 2005
Iron and copper are essential nutrients, excesses or deficiencies of which cause impaired cellular functions and eventually cell death. The metabolic fates of copper and iron are intimately related. Systemic copper deficiency generates cellular iron deficiency, which in humans results in diminished work capacity, reduced intellectual capacity ...
Miguel, Arredondo, Marco T, Núñez
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Iron and copper are essential nutrients, excesses or deficiencies of which cause impaired cellular functions and eventually cell death. The metabolic fates of copper and iron are intimately related. Systemic copper deficiency generates cellular iron deficiency, which in humans results in diminished work capacity, reduced intellectual capacity ...
Miguel, Arredondo, Marco T, Núñez
openaire +2 more sources
Comparative metabolism of copper
Journal of the American Veterinary Medical Association, 1987Copper is required in trace amounts for many body functions. The prominent effects of Cu deficiency or Cu toxicosis differs greatly between animal species. Along with iron, Cu is necessary for the transfer of O2 via a cascade of enzymes so that energy may be available for vital body functions without overheating of the tissues through rapid oxidation ...
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Journal of the American Medical Association, 1956
Copper as a remedy for various ailments has been of interest to physicians for many hundreds of years. It was first recognized as a normal constituent of human blood in 1875, 1 but it was not until 1924 that Elvehjem and coworkers demonstrated the essential nature of copper in mammalian nutrition, particularly in erythropoiesis.
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Copper as a remedy for various ailments has been of interest to physicians for many hundreds of years. It was first recognized as a normal constituent of human blood in 1875, 1 but it was not until 1924 that Elvehjem and coworkers demonstrated the essential nature of copper in mammalian nutrition, particularly in erythropoiesis.
openaire +2 more sources