Results 151 to 160 of about 264,643 (200)

Oral Contraceptives and Copper Metabolism

Nature, 1970
It has been known for many years that serum copper is increased during the later stages of pregnancy. Exogenous oestrogens produce an increase in both serum copper and the copper-binding globulin ceruloplasmin and it is therefore not surprising that that all of the popular oral contraceptives containing potent synthetic oestrogens have been reported ...
M, Briggs, J, Austin, M, Staniford
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Genetic disorders of copper metabolism

Current Opinion in Pediatrics, 1994
In this review we discuss four genetic disorders of copper metabolism. Wilson's disease and Indian childhood cirrhosis result from the toxic effects of copper accumulation in the liver. Menkes' disease and, most likely, occipital horn syndrome result from copper deficiency secondary to disturbances in copper transport. The recent cloning and sequencing
K, Petrukhin, T C, Gilliam
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Ceruloplasmin: Copper Metabolism

1980
Ceruloplasmin (ferroxidase I) first described in 1948, is the blue copper-containing oxidase present in the α2-globulin fraction of human serum (see Figure 3.5, Table 3.1). Close to 95% of the serum copper is located in this fraction.(1,2) The molecular weight of the major form of ceruloplasmin, referred to as ceruloplasmin I, is 134,000 ± 3000.(3 ...
Samuel Natelson, Ethan A. Natelson
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Abnormal copper metabolism

Neurology, 1988
We describe a patient with extrapyramidal neurologic disease and an abnormal copper profile with hepatic copper accumulation, but no cirrhosis histologically, thus excluding a diagnosis of Wilson's disease (WD). We compared and highlighted the differences between similar previously reported cases of abnormal copper metabolism and true WD and suggest a ...
J, Heckmann, D, Saffer
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Metabolic Disorders of Copper Metabolism

1977
Copper, atomic number 29, is an extremely versatile element both outside and inside living cells. The malleability, ductility, and esthetic properties of copper have promoted its use in pottery, ornaments, and currency for centuries. During the more recent decades, the electrical conductivity of copper has had an important role in the advancement of ...
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Metallothionein in Intestinal Copper Metabolism

1979
Approximately a decade after Margoshes and Vallee (1) first identified metallothionein, Evans et al. (2) suggested that this sulfhydryl-rich protein may be involved in the metabolism of copper in both the liver and the intestine. Recently, Bremner and Young (3) demonstrated that copper is bound to metallothionein in mammalian liver. Subsequently, after
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Zinc Interference With Copper Metabolism

JAMA: The Journal of the American Medical Association, 1978
Elsewhere in this issue ofThe Journal, Prasad et al (p 2166) describe a manifestation of the toxic effects of zinc in humans that has not been generally appreciated. They report the occurrence of copper deficiency (hypocupremia, leukopenia, and anemia) in a patient treated with ten times the recommended dietary allowance for zinc 1 during a prolonged ...
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COPPER METABOLISM

Pharmacological Reviews, 1960
I H, SCHEINBERG, I, STERNLIEB
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Copper metabolism and pediatric cholestasis

Current Opinion in Clinical Nutrition and Metabolic Care, 2011
Copper is an essential trace mineral but both deficiency and toxicity need to be avoided. Copper is regulated via excretion by the biliary system and caution was recommended when administered in patients with cholestasis. Recent clinical reports indicate that despite the cholestasis, copper should not be withheld from parenteral nutrition.Transporters ...
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Copper Metabolism and Epilepsy: A Preliminary Report

Epilepsia, 1966
SUMMARYA comparison is made between the total copper level in the blood of epileptic and asthmatic patients, who have got the same diet during two weeks. A significant higher copper level is found in the epileptic patients, which is a further support of the work of Canelas et al.RÉSUMÉL'auther fait une comparaison du taux de cuivre total dans le sang ...
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