Results 171 to 180 of about 267,849 (342)

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

open access: yesAdvanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou   +10 more
wiley   +1 more source

Effects of Dietary Copper Source and Level on Performance, Carcass Characteristics and Lipid Metabolism in Lambs [PDF]

open access: gold, 2008
Jianbo Cheng   +6 more
openalex   +1 more source

Effects of Dietary Glucose and Fructose on Copper, Iron, and Zinc Metabolism Parameters in Humans [PDF]

open access: gold, 2020
Nathaniel H. O. Harder   +10 more
openalex   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

Copper metabolism-related biomarkers and therapeutic targets for diabetic nephropathy. [PDF]

open access: yesPeerJ
Yan Q   +11 more
europepmc   +1 more source

Copper metabolism in cell death and autophagy. [PDF]

open access: yesAutophagy, 2023
Xue Q   +5 more
europepmc   +1 more source

MXene/Carboxymethyl Chitosan Moisture Responsive Soft Actuator with Diode‐Like Actuation for Versatile Applications Driven by Human Metabolism

open access: yesAdvanced Science, EarlyView.
A MXene‐based actuator with gradient thickness is fabricated by a novel and simple vacuum‐assisted “tilt‐filtration” approach. The actuator exhibits a “diode‐like” controllable unidirectional deformation behavior under moisture gradient, and its deformation direction is strictly correlated to its thickness gradient direction and moisture source ...
Liangliang Xu   +7 more
wiley   +1 more source

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