Results 81 to 90 of about 4,483,351 (293)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Segmentation and Clustering of Local Planimetric Distortion Patterns in Historical Maps of Jerusalem
ISPRS International Journal of Geo-InformationThe advancement of computational tools for cartometric analysis has opened new avenues for the identification and understanding of stemmatic relationships between historical maps through the analysis of their planimetric distortions.
Beatrice Vaienti +2 more
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Borrowed Beauties: The National Collection of Artistic Reproductions
Culture & History Digital Journal, 2013 The role of the copy in the history of art; museums of art reproductions and the Spanish collection at the end of the 19th century; the phenomenon of the copy in ancient Rome and in the successive rebirths and recoveries of the classic in the Western ...
María Bolaños
doaj +1 more source
Quantum state restoration and single-copy tomography
, 2010 Given a single copy of an n qubit quantum state |psi>, the no-cloning theorem greatly limits the amount of information which can be extracted from it. Moreover, given only a procedure which verifies the state, for example a procedure which measures the ...
Andrew Lutomirski +9 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Increased gene copy number of DEFA1/DEFA3 worsens sepsis by inducing endothelial pyroptosis. [PDF]
, 2019 Sepsis claims an estimated 30 million episodes and 6 million deaths per year, and treatment options are rather limited. Human neutrophil peptides 1-3 (HNP1-3) are the most abundant neutrophil granule proteins but their neutrophil content varies because ...
Chen, QiXing +12 more
core +1 more source
The classical double copy in maximally symmetric spacetimes
, 2018 The classical double copy procedure relates classical asymptotically-flat gravitational field solutions to Yang-Mills and scalar field solutions living in Minkowski space.
Carrillo-Gonzalez, Mariana +2 more
core +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source