Results 31 to 40 of about 9,837,393 (260)
Copy number variation across European populations.
PLoS ONE, 2011 Genome analysis provides a powerful approach to test for evidence of genetic variation within and between geographical regions and local populations. Copy number variants which comprise insertions, deletions and duplications of genomic sequence provide ...
Wanting Chen +10 more
doaj +1 more source
Trf4 targets ncRNAs from telomeric and rDNA spacer regions and functions in rDNA copy number control [PDF]
, 2007 Trf4 is the poly(A) polymerase component of TRAMP4, which stimulates nuclear RNA degradation by the exosome. We report that in Saccharomyces cerevisiae strains lacking Trf4, cryptic transcripts are detected from regions of repressed chromatin at ...
Houseley, Jonathan +3 more
core +1 more source
Adaptive copy number evolution in malaria parasites. [PDF]
PLoS Genetics, 2008 Copy number polymorphism (CNP) is ubiquitous in eukaryotic genomes, but the degree to which this reflects the action of positive selection is poorly understood.
Shalini Nair +9 more
doaj +1 more source
Identification and characterization of disease-related copy number variations (CNVs) by high-dense SNP oligonucleotide microarrays [PDF]
, 2012 Genomic microarray analysis is rapidly replacing conventional chromosome analysis by molecular karyotyping due to the significant increase in the power to detect causative CNVs.
Rivera Brugués, Núria
core +6 more sources
Copy number variation of Fc gamma receptor genes in HIV-infected and HIV-tuberculosis co-infected individuals in Sub-Saharan Africa [PDF]
, 2013 AIDS, caused by the retrovirus HIV, remains the largest cause of morbidity in sub-Saharan Africa yet almost all genetic studies have focused on cohorts from Western countries.
F. Mugusi (7640813) +76 more
core +2 more sources
Copy Number Profiling of Brazilian Astrocytomas
G3: Genes, Genomes, Genetics, 2016 Copy number alterations (CNA) are one of the driving mechanisms of glioma tumorigenesis, and are currently used as important biomarkers in the routine setting.
Lucas Tadeu Bidinotto +12 more
doaj +1 more source
Copy-number profiles of AGMK1-9T7 cells at different passages.
, 2022 A. DNA copy-number profiles of four passages of AGMK1-9T7 cells hybridized onto a human oaCGH microarray, relative to a common reference sample (AGMK1-9T7 cells at passage 3). The x-axis indicates the location of each arrayed target sequence in the human
Matthew Breen (688338) +8 more
core +1 more source
BMC Genomics, 2012 Background Copy number variation (CNV) is a major source of structural variants and has been commonly identified in mammalian genome. It is associated with gene expression and may present a major genetic component of phenotypic diversity.
Chen Congying +7 more
doaj +1 more source
Copy number variation in the horse genome. [PDF]
PLoS Genetics, 2014 We constructed a 400K WG tiling oligoarray for the horse and applied it for the discovery of copy number variations (CNVs) in 38 normal horses of 16 diverse breeds, and the Przewalski horse.
Sharmila Ghosh +11 more
doaj +1 more source
Copy Number Variation in Inflammatory Breast Cancer
Cells, 2023 Identification of a unique genomic biomarker in de novo inflammatory breast cancer (IBC) may provide an insight into the biology of this aggressive disease. The goal of our study was to elucidate biomarkers associated with IBC.
Aditi Hazra +7 more
doaj +1 more source