Results 61 to 70 of about 12,151 (175)

Ferroptosis and Its Emerging Role in Gestational Diabetes Mellitus

open access: yesMedicine Advances, EarlyView.
Ferroptosis contributes to the development of gestational diabetes mellitus (GDM) through iron overload, lipid peroxidation, and antioxidant system disruption. These changes impair adipocyte and β‐cell function, promoting insulin resistance and hyperglycemia.
Jinfeng Xu   +4 more
wiley   +1 more source

Extraction in Coq: An Overview [PDF]

open access: yes, 2008
The extraction mechanism of Coq allows one to transform Coq proofs and functions into functional programs. We illustrate the behavior of this tool by reviewing several variants of Coq definitions for Euclidean division, as well as some more advanced examples.
openaire   +2 more sources

PFOA Exposure Elicits Quantitative Lipidomic Changes in the Pancreas in a Mouse Model of Pancreatic Cancer

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley   +1 more source

uds-psl/coq-library-undecidability: Coq Library of Undecidability Proofs version 1.0.1

open access: yes, 2022
This release is intended to serve as the base for a release of coq-library-complexity.1.0+8.16.
Yannick Forster   +8 more
core   +1 more source

Opposing roles of DGAT‐mediated lipid droplet biogenesis in the regulation of ferroptosis sensitivity

open access: yesThe FEBS Journal, EarlyView.
Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump   +10 more
wiley   +1 more source

Treatment of CoQ(10) deficient fibroblasts with ubiquinone, CoQ analogs, and vitamin C: time- and compound-dependent effects.

open access: yesPLoS ONE, 2010
BackgroundCoenzyme Q(10) (CoQ(10)) and its analogs are used therapeutically by virtue of their functions as electron carriers, antioxidant compounds, or both.
Luis C López   +8 more
doaj   +1 more source

New Insights on the Uptake and Trafficking of Coenzyme Q

open access: yesAntioxidants, 2023
Coenzyme Q (CoQ) is an essential lipid with many cellular functions, such as electron transport for cellular respiration, antioxidant protection, redox homeostasis, and ferroptosis suppression.
Michael D. Guile   +3 more
doaj   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

open access: yesThe FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney   +10 more
wiley   +1 more source

mattam82/Coq-Equations: Equations v1.2-beta for Coq 8.9

open access: yes, 2019
<p>Release 1.2beta of Coq-Equations, see announcement here:</p> <p><a href="http://mattam82.github.io/Coq-Equations/equations/2019/01/28/1.2beta.html">http://mattam82.github.io/Coq-Equations/equations/2019/01/28/1.2beta.html</a&
Matthieu Sozeau   +12 more
core   +1 more source

The Coq Proof Assistant : Reference Manual : Version 7.2 [PDF]

open access: yes, 2002
Coq is a proof assistant based on a higher-order logic. Coq allows to handle calculus mathematical assertions and to check mechanically proofs of these assertions.
Coq, The
core   +1 more source

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