Results 11 to 20 of about 255,530 (261)

Sequence Analysis of Mitochondrial DNA Hypervariable Regions Using Infrared Fluorescence Detection

BioTechniques, 1998
The non-coding region of the mitochondrial genome provides an attractive target for human forensic identification studies. Two hypervariable (HV) regions, each approximately 250–350 bp in length, contain the majority of mitochondrial DNA (mtDNA) sequence
David L. Steffens, Reena Roy
doaj   +1 more source

Cerámica y vibración de la luz. Nuevas técnicas de nacarado e irisado y caracterización colorimétrica

Informes de la Construccion, 2016
Los materiales cerámicos han abierto nuevos espacios de innovación en su aplicación en las envolventes de los edificios en los últimos años. Sin embargo, ha sido escasa la investigación en su relación con la vibración de la luz, la percepción visual y su
V. Echarri Iribarren, A. B. González Avilés, M. Ródenas, J. Olivares   +3 more
doaj   +1 more source

Negotiated Resilience and the Trust-Performance Gap in Flood-Prone Shoreline Barangays of Digos City, Philippines

Journal of Arts, Humanities and Social Science
Coastal flooding remains a recurring threat in the shoreline barangays of Digos City, where hazard exposure intersects with livelihood insecurity, weak infrastructure, and uneven institutional response. This study examines how residents of Aplaya, Cogon-
Jeremiah Blaise D. Andrade, Johnrich Antoni D. Buhisan, Jellou S. Castillo, Junje A. Cedeño, Ella Mae N. Llena, John Royce T. Mistula, Crizyl Jane N. Paquera, Abegail Faye L. Peñaruya, Joselito B. Ponce de Leon Jr., Charles D. Sarabillo, Alan B. Alejandrino, Archangelo D. Alegado, Rommel V. Recla   +12 more
doaj   +1 more source

The benefits of digital thoracic drainage system for outpatients undergoing pulmonary resection surgery

Revista Portuguesa de Pneumologia, 2011
Since digital thoracic drainage system (DTDS) came onto the market, a number of its advantages have become clear, for example that of eliminating the differences between observers.
J.M. Mier, J.J. Fibla, L. Molins
doaj   +1 more source

Vertigo in Acute Stroke Is a Predictor of Brain Location but Is Not Related to Early Outcome: The Experience of Sagrat Cor Hospital of Barcelona Stroke Registry

Biomedicines, 2022
Background: Vertigo is an uncommon symptom among acute stroke victims. Knowledge about the clinical profile, the brain location, and the early outcome in stroke patients with cerebrovascular diseases and vertigo remains limited. Objectives: In this study,
Angela d’Annunzio, Adrià Arboix, Luís García-Eroles, María-José Sánchez-López   +3 more
doaj   +1 more source

Challenges and Coping Mechanisms of High School English Language Learners and their PISA Performance

International Journal of Multidisciplinary Educational Research and Innovation
This study explored the multifaceted experiences of high school English language learners (HS-ELLs) in a local public high school, focusing on their challenges, coping mechanisms, and institutional support systems.
Louise Jermie C. Pantig, Decei Grace D. Agbay, Kervy Erl G. Estampa, Jay C. Pacis, Crea Mae C. Severillas, Maria Elena C. Morales, Lorenzo Jr. I. Balili   +6 more
doaj   +1 more source

AF driver detection in pulmonary vein area by electropcardiographic imaging: Relation with a favorable outcome of pulmonary vein isolation

Frontiers in Physiology, 2023
Pulmonary vein isolation (PVI) is the most successful treatment for atrial fibrillation (AF) nowadays. However, not all AF patients benefit from PVI.
Carlos Fambuena-Santos, Ismael Hernández-Romero, Rubén Molero, Felipe Atienza, Felipe Atienza, Andreu M. Climent, M S. Guillem   +6 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source