Results 41 to 50 of about 255,296 (262)

Arrhythmia prevention protocol during papaverine administration for invasive coronary functional assessment

Frontiers in Cardiovascular Medicine
BackgroundAccurate assessment of coronary physiology through invasive functional testing is critical for the effective management of chronic coronary syndromes. The induction of maximal and sustained coronary hyperemia is essential for obtaining reliable
Dobrin Vassilev, Dobrin Vassilev, Niya Mileva, Niya Mileva, Gavril Stoev, Ilter Pazardzhykly, Panayot Panayotov, Panayot Panayotov, Gianluca Rigatelli, Valery Gelev   +9 more
doaj   +1 more source

Therapy with Ulipristal Acetate in a Hypertensive Patient

Case Reports in Medicine, 2018
Ulipristal acetate (UPA) is a medical therapy for patients with symptomatic uterine fibroids. The drug has shown efficacy in the control of heavy menstrual bleeding and, as a consequence, in anaemia improvement.
A. Alcalde Dominguez, J. Rabasa Antonijuan, M. Cusidó Gimferrer, M. Jiménez Ortuño   +3 more
doaj   +1 more source

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

Advanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao, Qianting Zhang, Wei Xu, Anxuan Fang, Haomang Xu, Cheng Qiu, Lugeng He, Chao Yu   +7 more
wiley   +1 more source

Visual Disturbances to Avatar Foot Position Increase Step-Width Variability in Immersive VR Treadmill Walking

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Gait variability, the subtle fluctuations in walking patterns, is crucial for adaptation and motor learning. While existing methods to increase gait variability often rely on force-based perturbations, these can reduce motivation.
Alex van den Berg, Katherine L. Poggensee, David Abbink, Laura Marchal-Crespo   +3 more
doaj   +1 more source

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

Advanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong, Yidan Wang, Simeng Lv, Zishan Dong, Kaixi Zhi, Xiuhua Guo, Xuyan Li, Ruoxi Yu, Yiyi Zhang, Siyuan Cheng, Chuan Wang   +10 more
wiley   +1 more source

Factores asociados a estrés percibido en trabajadores del Hospital Sagrat Cor – Martorell durante la atención a la pandemia Covid-19

Psicosomática y Psiquiatría, 2021
C Avella-Garcia, R Salvador, D Paiva, A Martínez-Muelas, A Magariño, S Pérez, M Vergel, A Ayala, T Baena, J Gómez, M Sánchez   +10 more
doaj   +1 more source

Limited matching of the cardiac output response to the peripheral demand of heat stress and exercise

Experimental Physiology
It is widely accepted that cardiac output matches the prevailing peripheral demand in healthy humans. However, it remains unknown whether stroke volume and heart rate are regulated interdependently to arrive at a specific cardiac output.
Moritz Lampkemeyer, Jonas Kell, Veit Börß, Tobias Claussen, Fabian Spahiu, Michelle Ottlik, Lars C. Helbig, Craig G. Crandall, Eric J. Stöhr   +8 more
doaj   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Diferencias intersexuales de las conductas alimentarias desadaptativas y la evolución de la obesidad en los candidatos de la cirugía bariátrica

Psicosomática y Psiquiatría, 2021
Laura Pajares, David Morillo, Joan Seguí, Núria Roca, Javier Foncillas, Rosa Morinigo, Aide De Arriba-Arnau, Luís Fernando Alguacil, Marian Monteverde   +8 more
doaj   +1 more source

O uso de cores em cilindros contendo gás: uma análise sobre a percepção visual sob diferentes iluminantes Color use in gas cylinders: a visual perception analysis under different lighting

Production, 2006
Este artigo apresenta uma análise sobre a percepção visual humana das cores adotadas na indústria. Para tanto, foi desenvolvido um ambiente experimental no qual objetos, simulando cilindros contendo gases, com cores variadas foram submetidos a diferentes
Fabiana Rodrigues Leta, Márcia Pimenta Velloso, Andrea Rozendo M. dos Santos   +2 more
doaj   +1 more source