Results 41 to 50 of about 255,530 (261)
This study reveals a metabolic signaling axis in the OSCC microenvironment where palmitic acid (PA) drives the activation of CAFs. PA uptake triggers CEBPG‐dependent epigenetic remodeling to upregulate ERN1 and TMBIM6, thereby mitigating ER stress. This adaptive program sustains CAF survival and the pro‐metastatic phenotype, establishing this pathway ...
Yiling Duan +6 more
wiley +1 more source
Limited matching of the cardiac output response to the peripheral demand of heat stress and exercise
It is widely accepted that cardiac output matches the prevailing peripheral demand in healthy humans. However, it remains unknown whether stroke volume and heart rate are regulated interdependently to arrive at a specific cardiac output.
Moritz Lampkemeyer +8 more
doaj +1 more source
BackgroundAccurate assessment of coronary physiology through invasive functional testing is critical for the effective management of chronic coronary syndromes. The induction of maximal and sustained coronary hyperemia is essential for obtaining reliable
Dobrin Vassilev +9 more
doaj +1 more source
Therapy with Ulipristal Acetate in a Hypertensive Patient
Ulipristal acetate (UPA) is a medical therapy for patients with symptomatic uterine fibroids. The drug has shown efficacy in the control of heavy menstrual bleeding and, as a consequence, in anaemia improvement.
A. Alcalde Dominguez +3 more
doaj +1 more source
Resistant Peanut Genotype Reprograms Rhizosphere Metabolism to Enhance Bacterial Wilt Suppression
The resistant peanut genotype selectively recruits beneficial bacteria, which coincides with the activation of salicylic acid (SA)‐dependent systemic acquired resistance (SAR) against Ralstonia solanacearum. Keystone rhizosphere metabolites are positively correlated with both beneficial microbiome assembly and SAR gene expression.
Rui Ren +20 more
wiley +1 more source
Gait variability, the subtle fluctuations in walking patterns, is crucial for adaptation and motor learning. While existing methods to increase gait variability often rely on force-based perturbations, these can reduce motivation.
Alex van den Berg +3 more
doaj +1 more source
Este artigo apresenta uma análise sobre a percepção visual humana das cores adotadas na indústria. Para tanto, foi desenvolvido um ambiente experimental no qual objetos, simulando cilindros contendo gases, com cores variadas foram submetidos a diferentes
Fabiana Rodrigues Leta +2 more
doaj +1 more source
The Spatiotemporal Genetic Architecture of Seed Vigor in Upland Cotton
Leveraging the semi‐automated SeedRanger platform, we profiled the germination kinetics of 356 cotton accessions at a 30‐min interval. This high‐throughput phenomic approach delineated a temporal genetic network comprising 541 stage‐specific loci. Crucially, functional validation identified FLA2 as a pivotal, auxin‐modulated regulator that orchestrates
Luyao Wang +32 more
wiley +1 more source
Este trabalho tem, como objetivo, comparar concentrados protéicos de folhas de mandioca produzidos por diferentes métodos e propor procedimento de obtenção com maior rendimento, conteúdo e recuperação protéica, menor teor de taninos e cor mais clara ...
Carla R. P. A. Teo +3 more
doaj +1 more source

