Results 51 to 60 of about 255,530 (261)

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan, Qian Zheng, Deng Liu, Ruichao Nie, Menglin Yao, Xiaolong Tang, Renjie Xu, Jinghong Xian, Wenjun Meng, Wenxin Luo, Dan Liu, Guiyi Ji   +11 more
wiley   +1 more source

Diferencias intersexuales de las conductas alimentarias desadaptativas y la evolución de la obesidad en los candidatos de la cirugía bariátrica

Psicosomática y Psiquiatría, 2021
Laura Pajares, David Morillo, Joan Seguí, Núria Roca, Javier Foncillas, Rosa Morinigo, Aide De Arriba-Arnau, Luís Fernando Alguacil, Marian Monteverde   +8 more
doaj   +1 more source

Cor Triatriatum [PDF]

Clinical Cardiology, 2010
Miguel A, Navas Lobato, Angel, Sanchez-Recalde, Roberto, Martin Reyes, Pilar, Luruena Lobo, Montse, Bret Zurita, Rafael, Pinado Peinado, Mar, Moreno Yanguela, Jose María, Oliver Ruiz   +7 more
openaire   +2 more sources

SPADE: A Deep Learning Framework for Spatial Mapping and Quantitative Cell–Cell Interaction Inference

Advanced Science, EarlyView.
SPADE integrates spatial transcriptomics with single‐cell RNA sequencing by using cell–cell communications (CCC) as a guide for spatial mapping. It improves cell‐type localization, enhances sparse gene‐expression signals, and reveals CCC programs at single‐spot resolution.
Xinyi Li, Ning Zhang, Zijie Jin
wiley   +1 more source

Natural Variation of COLD and CATECHINS REGULATOR 1 Coordinately Fine‐Tunes Cold Tolerance and Tea Quality in Tea Plants

Advanced Science, EarlyView.
Multi‐trait genome‐wide association mapping identifies a central hub regulator, COLD AND CATECHINS REGULATOR 1 (CCR1), and its excellent natural allele variation, coordinately enhancing cold tolerance and promoting catechins biosyntheis. CsCCR1 interacts with CsCBF1/3 and is transcriptionally activated by CsLUX and CsKUA1 to promote catechins ...
Yanli Wang, Wei Tong, Qiong Wu, Didi Wu, Yanrui Zhang, Qijuan Gao, Fangdong Li, Zhaoliang Zhang, Wenjie Wang, Chuankui Song, Enhua Xia   +10 more
wiley   +1 more source

Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy

Advanced Science, EarlyView.
A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li, Daishi Li, Danyao Chen, Yating Dian, Lei Yao, Hui Su, Ziyu Guo, Deze Zhao, Zihua Wu, Furong Zeng, Chunfang Zhang, Guangtong Deng   +11 more
wiley   +1 more source

Suplementos enterales: ¿complementos o sustitutos de la dieta?

Nutrición Hospitalaria
Objetivo: Evaluar la utilización de suplementos nutricionales orales analizando el motivo de su prescripción y su implicación en el aporte calórico-proteico ingerido.
M. Martínez Sogues, M. Pons Busom, N. Roca Rossellini, M. Aguas Compaired, B. Eguileor Partearroyo   +4 more
doaj  

Influência das características tecnológicas na cor da madeira de eucaliptos.

Ciência Florestal, 2010
Devido à importância da cor da madeira como componente de descrição da mesma, é que se realizou um estudo procurando verificar a influência dos componentes químicos na cor da madeira de diferentes clones de eucaliptos. Foram verificadas as quantidades de
Cláudia Lopes Selvati de Oliveira Mori, Fábio Akira Mori, José Tarcísio Lima, Paulo Fernando Trugilho, Adalberto Caldas Oliveira   +4 more
doaj   +1 more source

CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano, Allen C. Luo, Paul Taufalele, Jenna A. Dombroski, Ehsan Aalaei, Schyler J. Rowland, Melissa S. Cantú, Alexandria T. Carter, Samantha V. Knoblauch, Cynthia A. Reinhart‐King, Michael R. King   +10 more
wiley   +1 more source

Potencialidade de processamento industrial de cultivares de batatas

Ciência Rural, 2015
A industrialização da batata tem sido limitada no Brasil, devido à falta de matéria-prima adequada, sendo a demanda suprida pelas importações de produtos processados.
Émerson Loli Garcia, Ezequiel Lopes do Carmo, Joaquim Gonçalves de Pádua, Magali Leonel   +3 more
doaj   +1 more source