Results 101 to 110 of about 672,839 (260)

Five Principles for the Development of Oncology Critical Care Medicine

Xiehe Yixue Zazhi
With the deep integration of tumor diagnosis and treatment technologies and critical care medicine, oncology critical care has emerged as an innovative interdisciplinary field, whose standardized development is crucial for improving the prognosis of ...
YU Zhengheng, ZHANG Zeyu, YANG Yanli
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

AI-Driven Network Optimization for the 5G-to-6G Transition: A Taxonomy-Based Survey and Reference Framework

Future Internet
This paper presents a taxonomy-based survey of AI-driven network optimization mechanisms relevant to the transition from fifth generation (5G) to sixth generation (6G) mobile communication systems.
Rexhep Mustafovski, Galia Marinova, Besnik Qehaja, Edmond Hajrizi, Shejnaze Gagica, Vassil Guliashki   +5 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Network analysis of depressive symptoms in Chinese outpatients with somatic symptom disorder

Frontiers in Psychiatry
BackgroundSomatic symptom disorder and depression in clinical practice are strongly correlated. In this study, network analysis was used to assess the depressive symptoms of patients with somatic symptom disorder to identify the most core and influential
Yihui Li, Junning Fang, Yunhui Zhong, Yibo Li, Yuanping Liao, Hong Tang   +5 more
doaj   +1 more source

Synergistic effects of E×B drifts and neutral recycling on core-edge integration for next-step fusion development

Abstract It is increasingly urgent to address core-edge integration issues for the design and construction of next-step fusion devices. Evidence of density shelf has appeared, for the first time, in the HL-2A tokamak with a closed, long-leg divertor configuration for the ion drift toward the magnetic X-point. The density shelf is manifested as
Hailong Du, Hailong Du, Houyang Guo, Na Wu, Huiqian Wang, Xavier Bonnin, Zengchen Yang, Bin Chen, Ze Yan, Dongmei Fan, Yulin Zhou, Lei Xue, Jiaxian Li, Shuo Wang, Miao Xue, Guoyao Zheng, Zhi Huang, Longwen Yan, Jinming Gao, Xiaoquan Ji, wei chen, Wulu Zhong, Min Xu, Dezhen Wang   +23 more
openaire   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Optoelectronic polymer memristors with dynamic control for power-efficient in-sensor edge computing

Light: Science & Applications
As the demand for edge platforms in artificial intelligence increases, including mobile devices and security applications, the surge in data influx into edge devices often triggers interference and suboptimal decision-making. There is a pressing need for
Jia Zhou, Wen Li, Ye Chen, Haowen Qian, Yen-Hung Lin, Ruipeng Li, Zhen Wang, Jin Wang, Wei Shi, Xianwang Tao, Youtian Tao, Haifeng Ling, Wei Huang, Mingdong Yi   +13 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source