Results 91 to 100 of about 150,909 (276)

"Europeanization of the core executive in the transition from circumstances of EU accession to full EU membership" [PDF]

open access: yes, 2005
Only recently have the direct and indirect ‘European’ impacts (of political outcomes at the European level) on domestic political systems started to be studied (i.e. Spanou, 1998; Bulmer and Burch, 1998 and 2001; Kassim, Peters and Wright, eds.
Fink-Hafner, Danica.
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Deployment and application of “5G+MEC”enabled intelligent manufacturing

open access: yesDianxin kexue, 2019
As one of the key techniques of 5G,MEC can localize the application and promote the deep integration of networks and services.In order to realize the application of “5G+MEC” in vertical industry,the 5G core network with service-based architecture was ...
Lingyi KONG
doaj   +2 more sources

Five Principles for the Development of Oncology Critical Care Medicine

open access: yesXiehe Yixue Zazhi
With the deep integration of tumor diagnosis and treatment technologies and critical care medicine, oncology critical care has emerged as an innovative interdisciplinary field, whose standardized development is crucial for improving the prognosis of ...
YU Zhengheng, ZHANG Zeyu, YANG Yanli
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

AI-Driven Network Optimization for the 5G-to-6G Transition: A Taxonomy-Based Survey and Reference Framework

open access: yesFuture Internet
This paper presents a taxonomy-based survey of AI-driven network optimization mechanisms relevant to the transition from fifth generation (5G) to sixth generation (6G) mobile communication systems.
Rexhep Mustafovski   +5 more
doaj   +1 more source

Study on the Integration of Human Performance and Accident Risk Assessment Models: Air-Midas & Topaz

open access: yes, 2005
A computational model of human performance (Air Man-machine Integration Design and Analysis System, Air MIDAS) and an accident risk assessment methodology (Traffic Organization and Perturbation AnalyZer, TOPAZ) were integrated in order to learn about the
Corker, Kevin
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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