Results 81 to 90 of about 672,839 (260)
High-resolution near-infrared images and moderate resolution spectra were obtained of the bipolar nebulae M~2--9 and AFGL 2688. The ability to spatially and spectrally resolve the various components of the nebulae has proved to be important in ...
Hora, Joseph L., Latter, William B.
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Research Advances in Decision-Making Technologies for Precision Pesticide Application in Crops
Global agricultural production is severely threatened by the intensification of crop diseases and pests. Traditional pesticide application methods, characterized by inefficiency and frequent phytotoxicity, necessitate the urgent development of smart ...
Xiaofu Feng +6 more
doaj +1 more source
Dynamic Peierls-Nabarro equations for elastically isotropic crystals
The dynamic generalization of the Peierls-Nabarro equation for dislocations cores in an isotropic elastic medium is derived for screw, and edge dislocations of the `glide' and `climb' type, by means of Mura's eigenstrains method.
Pellegrini, Yves-Patrick
core +3 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Automated Disassembly of Waste Printed Circuit Boards: The Role of Edge Computing and IoT
The ever-growing volume of global electronic waste (e-waste) poses significant environmental and health challenges. Printed circuit boards (PCBs), which form the core of most electronic devices, contain valuable metals as well as hazardous materials. The
Muhammad Mohsin +3 more
doaj +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Integrating AI and cloud-edge technologies for music creation in educational and performance domains
This paper provides a systematic exploration of Artificial Intelligence (AI) for music generation within a cloud-edge synergy architecture (i.e. a coordinated cloud–edge computing paradigm where the cloud handles compute-intensive training and high ...
Xue Fan, Wei Zou, M. K. Moghimi, Wei Yi
doaj +1 more source
OSNet: An Edge Enhancement Network for a Joint Application of SAR and Optical Images
The combined use of synthetic aperture radar (SAR) and optical images for surface observation is gaining increasing attention. Optical images, with their distinct edge features, can accurately classify different objects, while SAR images reveal deeper ...
Keyu Ma +6 more
doaj +1 more source

