Results 71 to 80 of about 672,839 (260)

High-order Discretization of a Gyrokinetic Vlasov Model in Edge Plasma Geometry

open access: yes, 2017
We present a high-order spatial discretization of a continuum gyrokinetic Vlasov model in axisymmetric tokamak edge plasma geometries. Such models describe the phase space advection of plasma species distribution functions in the absence of collisions ...
Colella, Phillip   +5 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

DIII-D research to provide solutions for ITER and fusion energy

open access: yesNuclear Fusion
The DIII-D tokamak has elucidated crucial physics and developed projectable solutions for ITER and fusion power plants in the key areas of core performance, boundary heat and particle transport, and integrated scenario operation, with closing the core ...
C.T. Holcomb   +667 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Mapping Observations of DNC and HN^13C in Dark Cloud Cores

open access: yes, 2003
We present results of mapping observations of the DNC, HN^13C, and H^13CO^+ lines (J=1-0) toward 4 nearby dark cloud cores, TMC-1, L1512, L1544, and L63, along with observations of the DNC and HN^13C lines (J=2-1) toward selected positions.
Gerin M.   +9 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Complete Wiener-Hopf Solution of the X-Ray Edge Problem

open access: yes, 1996
We present a complete solution of the soft x-ray edge problem within a field-theoretic approach based on the Wiener-Hopf infinite-time technique. We derive for the first time within this approach critical asymptotics of all the relevant quantities for ...
Janis, V.
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Two-Steps Slotting Method in Magnet Edge of PMG for Wind Energy Harvesting

open access: yesInternational Journal of Technology, 2020
This paper focuses on the study of how to decrease the value of the cogging torque in an Inset Permanen Magnet Generator. The permanent-magnet generator of an integral slot number with 24 slots and 8 poles was selected and investigated for the ...
Tajuddin Nur, Marsul Siregar
doaj   +1 more source

Core-edge integrated predictive studies of ST40 and NSTX plasmas with the scrape-off layer box model

open access: yesPhysics of Plasmas
The ability to model the interplay between the core and edge of tokamak plasmas is crucial to designing both the plasma operating scenario of a fusion pilot plant and the design of the tokamak itself. Scrape-off-layer (SOL) models that are tailored to integrated scenario modeling need to have fast turn-around time and minimal computational burden to ...
X. Zhang   +9 more
openaire   +1 more source

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