Results 51 to 60 of about 150,909 (276)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

SOLEDGE3X integrated core-edge modelling of tungsten sources, migration, and radiation in WEST plasmas

open access: yesNuclear Materials and Energy
The W impurity species was introduced in the multi-component edge fluid code SOLEDGE3X, in its 2D transport version. To do so, several physical ingredients have been implemented. Firstly, W gross erosion is calculated using the Garcia-Rosales formula, and W re-deposition is estimated with either a Groth–Tskhakaya formulation or a Neural Network trained
N. Varadarajan   +8 more
openaire   +2 more sources

Structural Schema Integration with Full and Partial Correspondence using Dual Model

open access: yes, 1992
he integration of views and schemas is an important part of database design and evolution and permits the sharing of data across complex applications. The view and schema integration methodologies used to date are driven purely by semantic considerations,
Geller, James   +3 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

State-of-the-art survey on resource optimization in edge computing

open access: yes大数据, 2019
The traditional centralized architecture,known as cloud computing,cannot accommodate such user demands in an efficient and timely manner.To cope with this problem,edge computing architectures have been proposed with the core concept of that“data ...
Zhihao QU   +4 more
doaj  

Europeanisation and Higher Education: Towards a Core Curriculum in European Studies? [PDF]

open access: yes, 2004
[From the Introduction]. As a policy area that remains primarily national in control and orientation, European co-operation in education policy has attracted relatively little attention from a political perspective.
Bache, Ian.
core  

Cue competition affects temporal dynamics of edge-assignment in human visual cortex [PDF]

open access: yes, 2011
Edge-assignment determines the perception of relative depth across an edge and the shape of the closer side. Many cues determine edge-assignment, but relatively little is known about the neural mechanisms involved in combining these cues.
Brooks, Joseph L, Palmer, Stephen E.
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

HIPED: machine learning framework for spherical tokamak pedestal prediction and optimization

open access: yesNuclear Fusion
We introduce a machine learning framework, HIPED (HeIght and width Predictor for Edge Dynamics), for predicting and optimizing pedestal and core performance in spherical tokamak plasmas.
J.F. Parisi   +6 more
doaj   +1 more source

Network Structure and Synergy Characteristics in the Guangdong-Hong Kong-Macao Greater Bay Area

open access: yesApplied Sciences
In regions where transportation and the economy are closely integrated, optimizing network structure and enhancing synergy are vital for regional integration.
Shaobo Wang   +4 more
doaj   +1 more source

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