Results 21 to 30 of about 80,540 (232)

Development and Application of Computing Architecture for Virtual‒Reality Integration [PDF]

中国工程科学
With the rapid evolution of virtual reality technologies such as digital twins, industrial Internet of Things, edge intelligence, and metaverse, virtual‒reality integration has become a core driving force for the construction of an intelligent society ...
Xiaohong Chen, Siyuan Gong, Yige Yuan, Wenzhi Cao, Fuqiang Wang   +4 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Simultaneous ELM suppression and divertor detachment via synergistic boron powder and neon injection in EAST

Nuclear Fusion
A novel approach for simultaneous power exhaust and edge-localized mode (ELM) control is presented in the Experimental Advanced Superconducting Tokamak discharges, which utilize an ITER-like tungsten divertor.
Zhen Sun, Rajesh Maingi, Wei Xu, Lei Peng, Kedong Li, Xin Lin, Yunxin Cheng, Donggui Wu, Fang Ding, Zhe Wang, Yanhong Guan, Minrui Wang, Yan Chao, Qingquan Yang, Kaifu Gan, Yuqiang Tao, Alessandro Bortolon, Huiqian Wang, Tianfu Zhou, Jia Huang, Wei Wang, Yifei Jin, Yanmin Duan, Yanzhen Xu, Ahmed Diallo, Kevin Tritz, Alexander Nagy, Hanna Schamis, Guizhong Zuo, Jinping Qian, Xianzu Gong, Jiansheng Hu, the EAST Team   +32 more
doaj   +1 more source

Advanced operation modes relying on core plasma turbulence stabilization in tokamak fusion devices

AAPPS Bulletin, 2023
Recent progress of advanced operation modes in tokamaks is addressed focusing upon internal transport barrier (ITB) discharges. These ITB discharges are being considered as one of candidate operation modes in fusion reactors.
Yong-Su Na
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Characterization of sedimentary and flow characteristics of shallow water delta front sand bodies: Xingshugang Oil Field, Daqing placanticline, Songliao Basin

Shiyou shiyan dizhi, 2020
The low degree of integration between relative permeability research and the sedimentary characteristics of sand bodies was studied. The sedimentary and flow characteristics of distributary channel microfacies and sheet sand microfacies in shallow water ...
Duanchuan LÜ, Jinpeng SONG
doaj   +1 more source

Autonomous continuous flow reactor synthesis for scalable atom-precision

Carbon Trends, 2023
With new instrumentation design, robotics, and in-operando hyphenated analytical tool automation, the intelligent discovery of synthesis pathways is becoming feasible. It can potentially bridge the gap for the scale-up of new materials. We review current
Bobby G. Sumpter, Kunlun Hong, Rama K. Vasudevan, Ilia Ivanov, Rigoberto Advincula   +4 more
doaj   +1 more source