Results 111 to 120 of about 9,087,341 (299)

The Common Core Debate [PDF]

open access: yes, 2014
The Common Core State Standards (CCSS) have ignited a passionate national debate about the standards that guide the education of our nation’s and state’s students.
Ash, Jennifer W.   +2 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

INFLUENCE OF HUMIDITY ON TECHNOLOGICAL PROPERTIES OF OAT GRAIN [PDF]

open access: yesТехника и технология пищевых производств, 2015
The relatively high gross oat grain yeild significantly reduced its government procurement. Poor equipment and technical base of farms, large financial costs do not allow to organize proper post-harvest grain processing for stabilization and improving ...
Mar’in V.A.   +2 more
doaj  

Stimulated resonant inelastic x-ray scattering with chirped, broadband pulses

open access: yes, 2018
We present an approach for initiating and tracing ultra-fast electron dynamics in core-excited atoms, molecules and solids. The approach is based on stimulated resonant inelastic x-ray scattering induced by a single, chirped, broadband XUV/x-ray pulse. A
Hollstein, Maximilian, Rohringer, Nina
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Core and edge modeling of JT-60SA H-mode highly radiative scenarios using SOLEDGE3X–EIRENE and METIS codes

open access: yesFrontiers in Physics
In its first phase of exploitation, JT-60SA will be equipped with an inertially cooled divertor, which can sustain heat loads of 10 MW/m2 on the targets for a few seconds, which is much shorter than the intended discharge duration. Therefore, in order to
L. De Gianni   +17 more
doaj   +1 more source

On simultaneous \(s\)-cores/\(t\)-cores

open access: yesDiscrete Mathematics, 2009
In this paper, the authors investigate the question of when a partition of n∈N is an s-core and also a t-core when s and t are not relatively prime. A characterization of all such s/t-cores is given, as well as a generating function dependent upon the polynomial generating functions for s/t-cores when s and t are relatively prime.
Sze, L, Aukerman, D, Kane, B
openaire   +3 more sources

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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