Results 91 to 100 of about 4,854,878 (287)

Leveraging core enzyme structures for microbiota targeted functional regulation: Urease as an example

iMeta
Microbial communities play critical roles in various ecosystems. Despite extensive research on the taxonomic and functional diversity of microbial communities, effective approaches to regulate targeted microbial functions remain limited. Here, we present
Shengguo Zhao, Huiyue Zhong, Yue He, Xiaojiao Li, Li Zhu, Zhanbo Xiong, Xiaoyin Zhang, Nan Zheng, Diego P. Morgavi, Jiaqi Wang   +9 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Lealtad, riqueza y autonomía en el Montevideo de las invasiones inglesas

Humanidades, 2006
Los doscientos años de las invasiones inglesas al Río de la Plata (1806-1807) suscitan la lectura que se hace desde la óptica de una de las ciudades afectadas: Montevideo.
Fernando Aguerre Core
doaj  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Element 3 Chairs and Course List Core General Education Assessment, 2017-2018

, 2018
The Chairs and Course List for Element 3 - Interdisciplinary Global Studies as part of the institution’s ongoing general education Core assessment ...
Undergraduate Core Oversight Committee, Wright State University
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Element 3 Assessment Report Template Core General Education Assessment, 2017-2018

, 2018
The Assessment Report Template for Element 3 - Interdisciplinary Global Studies as part of the institution’s ongoing general education Core assessment ...
Undergraduate Core Oversight Committee, Wright State University
core   +1 more source

Sedimentological Analysis of Well Data by the Example of the Dagi Horizon of the Northeastern Shelf of Sakhalin Island [PDF]

Учёные записки Казанского университета: Серия Естественные науки, 2016
Well logging methods provide important data on data on sedimentary structures, genesis of sedi-ments, and relations of the facies in sedimentary basins.
V.V. Rybal’chenko, D.Ya. Khabibullin, A.Yu. Petukhov, A.V. Davydov, V.N. Khoshtariya, S.E. Dmitriev, S.N. Khlanovskaya, A.F. Islamov, S.S. Egorov, R.I. Tukhtaev, R.R. Khasanov   +10 more
doaj  

To the core [PDF]

Journal of Thrombosis and Haemostasis, 2016
F R, Rosendaal, P H, Reitsma
openaire   +2 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source