Results 101 to 110 of about 3,820,570 (317)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Core and edge modeling of JT-60SA H-mode highly radiative scenarios using SOLEDGE3X–EIRENE and METIS codes

open access: yesFrontiers in Physics
In its first phase of exploitation, JT-60SA will be equipped with an inertially cooled divertor, which can sustain heat loads of 10 MW/m2 on the targets for a few seconds, which is much shorter than the intended discharge duration. Therefore, in order to
L. De Gianni   +17 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

MUS 1210 Music Listening Core General Education Assessment, 2023-2024

open access: yes, 2023
This report assesses Wright State University\u27s course MUS 1210, Music Listening, as part of the institution’s ongoing general education Core assessment ...
College of Liberal Arts, Wright State University
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Element 3 Chairs and Course List Core General Education Assessment, 2017-2018

open access: yes, 2018
The Chairs and Course List for Element 3 - Interdisciplinary Global Studies as part of the institution’s ongoing general education Core assessment ...
Undergraduate Core Oversight Committee, Wright State University
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

2020 Core Assessment Report

open access: yes, 2020
This report contains data across Wright State University course sections that were part of the 2020 Core ...
Wright State University
core  

ABOUT THE GEOMETRY AND THE APPLICATIONS OF THE TWISTED SURFACES

open access: yesJournal of Industrial Design and Engineering Graphics, 2015
The helical and spiral surfaces are used in various fields. These surfaces are obtained by rotating a segment line called generatrix around directrices lines, respectively the spiral surfaces are obtained by composing simultaneously the movements of ...
Carmen Marza   +2 more
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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