Results 111 to 120 of about 4,854,878 (287)
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
ABOUT THE GEOMETRY AND THE APPLICATIONS OF THE TWISTED SURFACES
Journal of Industrial Design and Engineering Graphics, 2015 The helical and spiral surfaces are used in various fields. These surfaces are obtained by rotating a segment line called generatrix around directrices lines, respectively the spiral surfaces are obtained by composing simultaneously the movements of ...
Carmen Marza +2 more
doaj
Terrorism and Political Violence, 2020 Is radicalization inherently conducive to terrorism? This paper addresses this fault-line within discourses on radicalization by analyzing the political awakening and mobilization of British Muslims operating in environments targeted by violent-extremists.
openaire +2 more sources
Element 3 UNOC Letter to Chairs Core General Education Assessment, 2017-2018
, 2018 The UNOC Letter to Chairs for Element 3 - Interdisciplinary Global Studies as part of the institution’s ongoing general education Core assessment ...
Wright State Core Oversight Committee, Wright State University
core
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
IMMANUEL WALLERSTEIN'S WORLD SYSTEM THEORY [PDF]
Annals of the University of Oradea: Economic Science, 2010 World-systems analysis is not a theory, but an approach to social analysis and social change developed, among others by the Immanuel Wallerstein. Professor Wallerstein writes in three domains of world-systems analysis: the historical development of the ...
Cosma Sorinel
doaj
Element 6 UCOC Letter to Chairs Core General Education Assessment, 2018-2019
, 2019 The UCOC Letter to Chairs for Element 6 - Natural Science as part of the institution’s ongoing general education Core assessment ...
Wright State Core Oversight Committee, Wright State University
core
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source