Results 31 to 40 of about 80,937 (249)

Impact of toroidal magnetic field direction on integrated ELM-stable operation and divertor power exhaust via boron powder injection in EAST

Nuclear Fusion
We report the first in-depth comparison of the impact of toroidal magnetic field direction on solid boron injection used for Edge-Localized Mode (ELM) control, power exhaust, and core high- Z impurity control in the Experimental Advanced Superconducting ...
Zhen Sun, Rajesh Maingi, Lei Peng, Xin Lin, Wei Xu, Zhe Wang, Qingquan Yang, Genfan Ding, Fang Ding, Kaifu Gan, Ahmed Diallo, Kevin Tritz, Tianfu Zhou, Yifeng Wang, Liang Chen, Kaixuan Ye, Wei Wang, Yunxin Cheng, Lingyi Meng, Yifei Jin, Ling Zhang, Yanmin Duan, Jizhong Sun, Alexander Nagy, Alessandro Bortolon, Guizhong Zuo, Jinping Qian, Xianzu Gong, Jiansheng Hu, the EAST Team   +29 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Progress at JET in integrating ITER-relevant core and edge plasmas within the constraints of an ITER-like wall

Plasma Physics and Controlled Fusion, 2015
This paper reports the progress made at JET-ILW on integrating the requirements of the reference ITER baseline scenario with normalized confinement factor of 1, at a normalized pressure of 1.8 together with partially detached divertor whilst maintaining these conditions over many energy confinement times.
Giroud, C, Jachmich, S, Jacquet, P, Järvinen, A, Lerche, E, Rimini, F, Aho Mantila, L, Aiba, N, Balboa, I, Belo, P, Angioni, C, Beurskens, M, Brezinsek, S, Casson, F. J, Coffey, I, Cunningham, G, Delabie, E, Devaux, S, Drewelow, P, Frassinetti, L, Figueiredo, A, Huber, A, Hillesheim, J, Garzotti, L, Goniche, M, Groth, M, Kim, Hyun Tae, Leyland, M, Lomas, P, Maddison, G, Marsen, S, Matthews, G, Meigs, A, Menmuir, S, Puetterich, T, van Rooij, G, Saarelma, S, Stamp, M, Urano, H, Webster, A, Abel, I., Afanesyev, V., Aftanas, M., Agarici, G., Aggarwal, K. M., Aho Mantila, L., Ahonen, E., Aints, M., Airila, M., Akers, R., Alarcon, T., Albanese, R., Alexeev, A., Alfier, A., Allan, P., Almaviva, S., Alonso, A., Alper, B., Altmann, H., Alves, D., Ambrosino, G., Amosov, V., Andersson, F., Anderssonsund ́en, E., Andreev, V., Andrew, Y., Angelone, M., Anghel, M., Anghel, A., Angioni, C., Apruzzese, G., Arcis, N., Arena, P., Argouarch, A., Ariola, M., Armitano, A., Armstrong, R., Arnoux, G., Arshad, S., Artaserse, G., Artaud, J. F., Ash, A., Asp, E., Asunta, O., Atanasiu, C. V., Atkins, G., Avotina, L., Axton, M. D., Ayres, C., Baciero, A., Bailescu, V., Baiocchi, B., Baker, R. A., Balboa, I., Balden, M., Balorin N. Balshaw, C. Balorin N. Balshaw, Banks, J. W., Baranov, Y. F., Barbier, D., Barlow, I. L., Barnard, M. A., Barnsley, R., Barrena, L., Barrera, L., Baruzzo, M., Basiuk, V., Bateman, G., Batistoni, P., Baumgarten, N., Baylor, L., Bazylev, B., Beaumont, P. S., Beausang, K., B ́ecoulet, M., Bekris, N., Beldishevski, M., Bell, A. C., Belli, F., Bellinger, M., Bellizio, T., Belo, P. S. A., Belonohy, E., Bennett, P. E., Benterman, N. A., Berger By, G., Bergsåker, H., Berk, H., Bernardo, J., Bernert, M., Bertrand, B., Beurskens, M. N. A., Bieg, B., Bienkowska, B., Biewer, T. M., Bigi, M., B ́ılkov ́a, P., Bin, W., Bird, J., Bizarro, J., Bj ̈orkas, C., Blackman, T. R., Blanchard, P., Blanco, E., Blum, J., Bobkov, V., Boboc, A., Boilson, D., Bolshakova, I., Bolzonella, T., Boncagni, L., Bonheure, G., Bonnin, X., Borba, D., Borthwick, A., Botrugno, A., Boulbe, C., Bouquey, F., Bourdelle, C., Bovert, K. V., Bowden, M., Boyce, T., Boyer, H. J., Bozhenkov, A., Brade, R. J., Bradshaw, J. M. A., Braet, J., Braic, V., Braithwaite, G. C., Brault, C., Breizman, B., Bremond, S., Brennan, P. D., Brett, A., Breue, J., Brezinsek, S., Bright, M. D. J., Briscoe, F., Brix, M., Brombin, M., Brown, B. C., Brown, D. P. D., Brzozowski, J., Bucalossi, J., Buckley, M. A., Budd, T., Budny, R. V., Bunting, P., Buratti, P., Burcea, G., Burckhart, A., Butcher, P. R., Buttery, R. J., Cahyna, P., Calabr`o, G., Callaghan, C. P., Caminade, J. P., Camp, P. G., Campling, D. C., Caniello, R., Canik, J., Romanelli, F., Thomas, P. D.   +201 more
  +9 more sources

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Modeling electron temperature profiles in the pedestal with simple formulas for ETG transport

Nuclear Fusion
This paper reports on the refinement (building on (Hatch D.R. et al 2022 Phys. Plasmas 29 062501)) and application of simple formulas for electron heat transport from electron temperature gradient (ETG) driven turbulence in the pedestal. The formulas are
D.R. Hatch, M.T. Kotschenreuther, P.-Y. Li, B. Chapman-Oplopoiou, J. Parisi, S.M. Mahajan, R. Groebner   +6 more
doaj   +1 more source

Advanced operation modes relying on core plasma turbulence stabilization in tokamak fusion devices

AAPPS Bulletin, 2023
Recent progress of advanced operation modes in tokamaks is addressed focusing upon internal transport barrier (ITB) discharges. These ITB discharges are being considered as one of candidate operation modes in fusion reactors.
Yong-Su Na
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Autonomous continuous flow reactor synthesis for scalable atom-precision

Carbon Trends, 2023
With new instrumentation design, robotics, and in-operando hyphenated analytical tool automation, the intelligent discovery of synthesis pathways is becoming feasible. It can potentially bridge the gap for the scale-up of new materials. We review current
Bobby G. Sumpter, Kunlun Hong, Rama K. Vasudevan, Ilia Ivanov, Rigoberto Advincula   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

SICAS, a new integrated divertor-SOL-pedestal-core framework for self-consistent modeling of ion and impurity transport in fusion devices

Nuclear Fusion
We present a new framework for core-edge integration studies named SICAS (SOLPS-ITER coupled to ASTRA-STRAHL) which enables high fidelity simulations of the core, edge, and divertor regions encompassing the transport of ions as well as the impurities ...
A. Welsh, L. Casali, E. Fable, J. Smiskey, R. Mattes, G. Tardini, B.T. Taczak   +6 more
doaj   +1 more source