Results 101 to 110 of about 3,964,850 (349)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Direct URCA-processes in neutron star quark core with strong magnetic field.

open access: yesEPJ Web of Conferences, 2017
Neutrino emissivity in direct URCA processes in superdense strongly magnetized quark medium is calculated. In calculations, we use the covariant method of density matrixes for charge fermions in uniform constant magnetic field.
Belyaev Vasily, Gvozdev Alexander
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Fast fossil rotation of neutron star cores

open access: yes, 2012
It is argued that the superfluid core of a neutron star super-rotates relative to the crust, because stratification prevents the core from responding to the electromagnetic braking torque, until the relevant dissipative (viscous or Eddington-Sweet) time ...
Melatos, A.
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Detecting the signal cycle of the deep Earth’s dynamic processes based on GRACE satellite and CHAOS-7 model data

open access: yesEarth and Planetary Physics
The GRACE (Gravity Recovery and Climate Experiment) space mission recorded temporal variation characteristics of the global gravity field at decadal timescales.
YongGang Zhang   +3 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Investigation of exit-velocity stratification effects on jets in a crossflow (STRJET) [PDF]

open access: yes, 1974
Program determines flow field about jets with velocity stratification exhausting into crossflow. Jets with three different types of exit-velocity stratification have been considered: (a) jets with relatively high-velocity core, (b) jets with relatively ...
Ziegler, H.
core   +1 more source

LBNL high field core program

open access: yes, 2011
4 pages, contribution to the EuCARD-AccNet-EuroLumi Workshop: The High-Energy Large Hadron Collider, Malta, 14 -- 16 Oct ...
openaire   +2 more sources

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