Results 81 to 90 of about 3,964,850 (349)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Earth, Planets and Space, 2023 The Earth’s magnetic field originated in the fluid core, the so-called core field, is the dominant contribution to the geomagnetic field. Since ancient times, the core geomagnetic field has been used primarily for geographical orientation and navigation ...
Marina Puente-Borque +4 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Zhongguo dianli, 2020 The noise of the transformer is mainly generated by the vibration of the oil tank, which is mainly generated by the vibration of the iron core, while the vibration of the iron core is mainly generated by the electromagnetic force.
Chao FAN +7 more
doaj +1 more source
Localization of electric field distribution in graded core-shell metamaterials
, 2009 The local electric field distribution has been investigated in a core-shell cylindrical metamaterial structure under the illumination of a uniform incident optical field.
Wei, En-Bo, Yu, K. W.
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Superconductive magnetic-field-trapping device [PDF]
, 1965 An apparatus which enables the establishment of a magnetic field in air that has the same intensity as the ones in ferromagnetic materials is described.
Elleman, D. D. +2 more
core +1 more source
The Evolution of Hot Topics in the field of Psychology in Virtual Reality Based on the Visualization Analysis of WOS Core Database (2011-2021) [PDF]
, 2023 Guoyu Liu, Zhifang He
openalex +1 more source