Results 41 to 50 of about 3,479,520 (326)
Genome Biology, 2014 Whole-genome sequences are now available for many microbial species and clades, however existing whole-genome alignment methods are limited in their ability to perform sequence comparisons of multiple sequences simultaneously. Here we present the Harvest
Todd J. Treangen +3 more
semanticscholar +1 more source
Journal of Infectious Diseases, 2020 Background Gonorrhea, caused by the bacterium Neisseria gonorrhoeae, is a globally prevalent sexually transmitted infection. The dynamics of gonococcal population biology have been poorly defined due to a lack of resolution in strain typing methods ...
O. Harrison +7 more
semanticscholar +1 more source
Frontiers in Microbiology, 2020 Whole genome sequencing (WGS) is increasingly used for epidemiological investigations of pathogens. While SNP variant calling is currently considered as the most suitable method, the choice of a representative reference genome and the isolate dependency ...
D. Blanc +4 more
semanticscholar +1 more source
Core Genome MLST for Source Attribution of Campylobacter coli. [PDF]
Front Microbiol, 2021 Campylobacter species are among the leading foodborne bacterial agents of human diarrheal illness. The majority of campylobacteriosis has been attributed to Campylobacter jejuni (85% or more), followed by Campylobacter coli (5–10%). The distribution of C. jejuni and C.
Harrison L +9 more
europepmc +7 more sources
Biology Open, 2022 Vibrio vulnificus is an opportunistic pathogen that naturally inhabits sea water globally and is responsible for most vibriosis-related deaths. The consumption of V.
Jie Li, Yiqing Zhu, Zhenxia Ma, Fu Yang
doaj +1 more source
Impact of Homologous Recombination on the Evolution of Prokaryotic Core Genomes [PDF]
mBio, 2019 Microbial populations exchange genetic material through a process called homologous recombination. Although this process has been studied in particular organisms, we lack an understanding of its differential impact over the genome and across microbes with different life-styles.
Josefa Antón +5 more
openaire +6 more sources
Accurate reconstruction of bacterial pan- and core- genomes with PEPPAN [PDF]
Genome Research, 2020 AbstractBacterial genomes can contain traces of a complex evolutionary history, including extensive homologous recombination, gene loss, gene duplications and horizontal gene transfer. In order to reconstruct the phylogenetic and population history of a set of multiple bacteria, it is necessary to examine their pan-genome, the composite of all the ...
Zhemin Zhou +2 more
openaire +6 more sources
Thermal proteome profiling in bacteria: probing protein state in vivo
Molecular Systems Biology, 2018 Increasing antibiotic resistance urges for new technologies for studying microbes and antimicrobial mechanism of action. We adapted thermal proteome profiling (TPP) to probe the thermostability of Escherichia coli proteins in vivo. E.
André Mateus +7 more
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Microbiology Spectrum, 2022 Staphylococcus aureus is a Gram-positive pathogen that causes various infections in humans and domestic animals. In China, S. aureus is the most common Gram-positive pathogen that causes clinical infections.
Zhen Xu, Chao Yuan
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Frontiers in Microbiology, 2020 Whole-genome sequencing (WGS)-based typing methods have emerged as promising and highly discriminative epidemiological tools. In this study, we combined gene-by-gene allele calling and core genome single nucleotide polymorphism (cgSNP) approaches to ...
E. Miró +8 more
semanticscholar +1 more source