Results 31 to 40 of about 558,921 (264)
Comparative Genomics Reveals the Core and Accessory Genomes of Streptomyces Species
The development of rapid and efficient genome sequencing methods has enabled us to study the evolutionary background of bacterial genetic information. Here, we present comparative genomic analysis of 17 Streptomyces species, for which the genome has been completely sequenced, using the pan-genome approach.
Ji-Nu, Kim +5 more
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Defining the core essential genome of Pseudomonas aeruginosa [PDF]
Genomics offered the promise of transforming antibiotic discovery by revealing many new essential genes as good targets, but the results fell short of the promise. While numerous factors contributed to the disappointing yield, one factor was that essential genes for a bacterial species were often defined based on a single or ...
Poulsen, Bradley E. +9 more
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Comparative genomics of 40 Weissella paramesenteroides strains
Weissella strains are often detected in spontaneously fermented foods. Because of their abilities to produce lactic acid and functional exopolysaccharides as well as their probiotic traits, Weissella spp.
Xing Wan +12 more
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Evolution of the core and pan-genome of Streptococcus: positive selection, recombination, and genome composition [PDF]
Abstract Background The genus Streptococcus is one of the most diverse and important human and agricultural pathogens. This study employs comparative evolutionary analyses of 26 Streptococcus genomes to yield an improved understanding of the relative roles of recombination and positive selection in ...
Lefébure, Tristan, Stanhope, Michael
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Phytochemicals: Extraction, Isolation, and Identification of Bioactive Compounds from Plant Extracts
There are concerns about using synthetic phenolic antioxidants such as butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA) as food additives because of the reported negative effects on human health.
Ammar Altemimi +4 more
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Eukaryotic pathogens display multiple mechanisms for breaching the blood-brain barrier (BBB) and invading the central nervous system (CNS). Of the fungal spp., that cause disease in mammals, only some cross brain microvascular endothelial cells which ...
Sarisa Na Pombejra +3 more
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Clustered Core- and Pan-Genome Content on Rhodobacteraceae Chromosomes [PDF]
Abstract In Bacteria, chromosome replication starts at a single origin of replication and proceeds on both replichores. Due to its asymmetric nature, replication influences chromosome structure and gene organization, mutation rate, and expression.
Karel Kopejtka +4 more
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Pantoea stewartii subsp. indologenes (Psi) is a causative agent of leafspot on foxtail millet and pearl millet; however, novel strains were recently identified that are pathogenic on onions. Our recent host range evaluation study identified two pathovars;
Gaurav Agarwal +2 more
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Impact of Homologous Recombination on the Evolution of Prokaryotic Core Genomes [PDF]
Microbial populations exchange genetic material through a process called homologous recombination. Although this process has been studied in particular organisms, we lack an understanding of its differential impact over the genome and across microbes with different life-styles.
González-Torres, Pedro +3 more
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Genomic environments scale the activities of diverse core promoters [PDF]
A classical model of gene regulation is that enhancers provide specificity whereas core promoters provide a modular site for the assembly of the basal transcriptional machinery. However, examples of core promoter specificity have led to an alternate hypothesis in which specificity is achieved by core promoters with different sequence motifs that ...
Clarice KY Hong, Barak A Cohen
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