Results 11 to 20 of about 558,921 (264)
Evolution of the orthopoxvirus core genome. [PDF]
Orthopoxviruses comprise several relevant pathogens, including the causative agent of smallpox and monkeypox virus. Analysis of orthopoxvirus genome evolution mainly focused on gene gains/losses. We instead analyzed core genes, which are conserved in all orthopoxviruses.
Molteni C +5 more
europepmc +5 more sources
An evolutionary view of the Fusarium core genome. [PDF]
Abstract Fusarium , a member of the Ascomycota fungi, encompasses several pathogenic species significant to plants and animals. Some phytopathogenic species have received special attention due to their negative economic impact on the agricultural industry around the world.
Gomez-Chavarria DA +2 more
europepmc +4 more sources
CoreDetector: a flexible and efficient program for core-genome alignment of evolutionary diverse genomes. [PDF]
Abstract Motivation Whole genome alignment of eukaryote species remains an important method for the determination of sequence and structural variations and can also be used to ascertain the representative non-redundant core-genome sequence of a population.
Fruzangohar M +3 more
europepmc +3 more sources
Analysis of the Core Genome and Pan-Genome of Autotrophic Acetogenic Bacteria [PDF]
Acetogens are obligate anaerobic bacteria capable of reducing carbon dioxide (CO2) to multicarbon compounds coupled to the oxidation of inorganic substrates, such as hydrogen (H2) or carbon monoxide (CO), via the Wood-Ljungdahl pathway. Owing to the metabolic capability of CO2 fixation, much attention has been focused on understanding the unique ...
Shin, Jongoh +3 more
openaire +3 more sources
The cyanobacterial genome core and the origin of photosynthesis [PDF]
Comparative analysis of 15 complete cyanobacterial genome sequences, including “near minimal” genomes of five strains of Prochlorococcus spp., revealed 1,054 protein families [core cyanobacterial clusters of orthologous groups of proteins (core CyOGs)] encoded in at least 14 of them.
Armen Y, Mulkidjanian +11 more
openaire +2 more sources
Impact of homologous recombination on core genome phylogenies [PDF]
Abstract Background Core genome phylogenies are widely used to build the evolutionary history of individual prokaryote species. By using hundreds or thousands of shared genes, these approaches are the gold standard to reconstruct the relationships of large sets of strains.
Caroline Marie Stott, Louis-Marie Bobay
openaire +3 more sources
Genome wide analysis of Arabidopsis core promoters [PDF]
Abstract Background Core promoters are the gene regulatory regions most proximal to the transcription start site (TSS), central to the formation of pre-initiation complexes and for combinatorial gene regulation. The DNA elements required for core promoter function in plants are poorly understood.
Molina Carlos, Grotewold Erich
openaire +3 more sources
Accurate reconstruction of bacterial pan- and core- genomes with PEPPAN [PDF]
Abstract Bacterial genomes can contain traces of a complex evolutionary history, including extensive homologous recombination, gene loss, gene duplications and horizontal gene transfer. In order to reconstruct the phylogenetic and population history of a set of multiple bacteria, it is necessary to examine their pan ...
Zhemin Zhou +2 more
openaire +3 more sources
The emergence of antimicrobial resistance (AMR) against third generation cephalosporins in Neisseria gonorrhoeae is a major public health concern, as these are antibiotics of last resort for the effective treatment of gonorrhea.
Jolinda de Korne-Elenbaas +4 more
openaire +4 more sources
Comparative genomics of Drosophila and human core promoters [PDF]
Abstract Background The core promoter region plays a critical role in the regulation of eukaryotic gene expression. We have determined the non-random distribution of DNA sequences relative to the transcriptional start site in Drosophila melanogaster promoters to identify sequences that may be biologically
FitzGerald, Peter C +4 more
openaire +2 more sources

