Results 41 to 50 of about 558,921 (264)

Comparative Genomics of the Aeromonadaceae Core Oligosaccharide Biosynthetic Regions [PDF]

International Journal of Molecular Sciences, 2017
Lipopolysaccharides (LPSs) are an integral part of the Gram-negative outer membrane, playing important organizational and structural roles and taking part in the bacterial infection process. In Aeromonas hydrophila, piscicola, and salmonicida, three different genomic regions taking part in the LPS core oligosaccharide (Core-OS) assembly have been ...
Gabriel Forn-Cuní, Susana Merino, Juan Tomás   +2 more
openaire   +3 more sources

Genomic Characterization of Lactobacillus delbrueckii Strains with Probiotics Properties

Frontiers in Bioinformatics, 2022
Probiotics are health-beneficial microorganisms with mainly immunomodulatory and anti-inflammatory properties. Lactobacillus delbrueckii species is a common bacteria used in the dairy industry, and their benefits to hosting health have been reported ...
Luís Cláudio Lima De Jesus, Flávia Figueira Aburjaile, Thiago De Jesus Sousa, Andrei Giacchetto Felice, Siomar De Castro Soares, Luiz Carlos Junior Alcantara, Luiz Carlos Junior Alcantara, Vasco Ariston De Carvalho Azevedo   +7 more
doaj   +1 more source

A genome triplication associated with early diversification of the core eudicots [PDF]

Genome Biology, 2012
Abstract Background Although it is agreed that a major polyploidy event, gamma, occurred within the eudicots, the phylogenetic placement of the event remains unclear. Results To determine when this polyploidization occurred relative to ...
Jiao, Y. N., Leebens-Mack, J., Ayyampalayam, S., Bowers, J. E., McKain, M. R., McNeal, J., Rolf, M., Ruzicka, D. R., Wafula, E., Wickett, N. J., Wu, X. L., Zhang, Y., Wang, J., Zhang, Y. T., Carpenter, E. J., Deyholos, M. K., Kutchan, T. M., Chanderbali, A. S., Soltis, P. S., Stevenson, D. W., McCombie, R., Pires, J. C., Wong, G. K. S., Soltis, D. E., dePamphilis, C. W.   +24 more
openaire   +4 more sources

Genetic Study of Severe Prolonged Lymphopenia in Multiple Sclerosis Patients Treated With Dimethyl Fumarate

Frontiers in Genetics, 2019
In delayed-release dimethyl fumarate (DMF)-treated patients, absolute lymphocyte count (ALC) often declines in the first year and stabilizes thereafter; early declines have been associated with development of severe prolonged lymphopenia (SPL). Prolonged
Dipen Sangurdekar, Chao Sun, Helen McLaughlin, Katherine Ayling-Rouse, Normand E. Allaire, Michelle A. Penny, Paola G. Bronson   +6 more
doaj   +1 more source

Genome sequence and pathogenicity of Vibrio vulnificus strain MCCC 1A08743 isolated from contaminated prawns

Biology Open, 2022
Vibrio vulnificus is an opportunistic pathogen that naturally inhabits sea water globally and is responsible for most vibriosis-related deaths. The consumption of V.
Jie Li, Yiqing Zhu, Zhenxia Ma, Fu Yang
doaj   +1 more source

Comparative genomics of the core and accessory genomes of 48 Sinorhizobiumstrains comprising five genospecies [PDF]

Genome Biology, 2013
Abstract Background The sinorhizobia are amongst the most well studied members of nitrogen-fixing root nodule bacteria and contribute substantial amounts of fixed nitrogen to the biosphere. While the alfalfa symbiont Sinorhizobium meliloti RM 1021 was one of the first rhizobial strains to be completely ...
Sugawara, Masayuki, Epstein, Brendan, Badgley, Brian D, Unno, Tatsuya, Xu, Lei, Reese, Jennifer, Gyaneshwar, Prasad, Denny, Roxanne, Mudge, Joann, Bharti, Arvind K, Farmer, Andrew D, May, Gregory D, Woodward, Jimmy E, Médigue, Claudine, Vallenet, David, Lajus, Aurélie, Rouy, Zoé, Martinez-Vaz, Betsy, Tiffin, Peter, Young, Nevin D, Sadowsky, Michael J   +20 more
openaire   +4 more sources

Using CRISPR/Cas9 for generation the cd209 knockout is a way to get cattle breeds resistant to the Bovine leukemia virus (BLV) [PDF]

E3S Web of Conferences, 2020
Bovine leukemia virus (BLV) causes enzootic leukemia - a chronic infectious disease occurring against the background of embedding the virus in the genome of B-lymphocytes and leading to malignization, invasion of tumor cells in organs and the formation ...
Deykin Alexey V., Kubekina Marina V., Silaeva Yulia Yu., Krivonogova Anna S., Isaeva Albina G.   +4 more
doaj   +1 more source

Genome-Wide Analysis of Ruminant Staphylococcus aureus Reveals Diversification of the Core Genome [PDF]

Journal of Bacteriology, 2008
ABSTRACT Staphylococcus aureus causes disease in humans and a wide array of animals. Of note, S. aureus mastitis of ruminants, including cows, sheep, and goats, results in major economic losses worldwide. Extensive variation in genome content exists among S.
Ben Zakour, Nouri, Sturdevant, Daniel E, Even, Sergine, Guinane, Caitriona M., Barbey, Corinne, Alves, Priscila D., Cochet, Marie-Françoise, Gautier, Michel, Otto, Michael, Fitzgerald, J. Ross, Le Loir, Yves   +10 more
openaire   +8 more sources

Clinical, Histopathological, and Molecular Characterization of Pediatric MN1::ZNF341‐Associated Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and
Thomas R. W. Oliver, Dyanne Rampling, Barbara Walkowiak, Nathaniel D. Anderson, Manas Dave, Henry Lee‐Six, Sadie Baskind, Pooja Balasubramanian, Glenn Anderson, Conor Parks, Toochi Ogbonnah, Emilia R. Robertson, Simon Hannam, Rohan Verma, John C. Achermann, Liina Palm, Neil Sebire, Thomas Jacques, Tom Watson, Carryl Dryden, Karin Straathof, Mette Jorgensen, Olga Slater, Sam Behjati, Sarita Depani, J. Ciaran Hutchinson   +25 more
wiley   +1 more source

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris, Priya B. Shetty, Olga A. Taylor, Elizabeth G. Atkinson, Melissa A. Richard, M. Monica Gramatges, Mark Zobeck, Sandi Pruitt, Amy Hughes, M. Brooke Bernhardt, Ashley Chavana, Van Huynh, Kathleen Ludwig, Laura Klesse, Kenneth Heym, Timothy Griffin, Rodrigo Erana, Juan Carlos Bernini, Han Chen, Bing Yu, Philip J. Lupo, Karen R. Rabin, Michael E. Scheurer, Austin L. Brown, The REDIAL Consortium   +24 more
wiley   +1 more source