Results 51 to 60 of about 4,042,841 (387)

iCN718, an Updated and Improved Genome-Scale Metabolic Network Reconstruction of Acinetobacter baumannii AYE. [PDF]

, 2018
Acinetobacter baumannii has become an urgent clinical threat due to the recent emergence of multi-drug resistant strains. There is thus a significant need to discover new therapeutic targets in this organism.
Kavvas, Erol, Monk, Jonathan M, Norsigian, Charles J, Palsson, Bernhard O, Seif, Yara   +4 more
core   +2 more sources

Genomic environments scale the activities of diverse core promoters [PDF]

Genome Research, 2021
A classical model of gene regulation is that enhancers provide specificity whereas core promoters provide a modular site for the assembly of the basal transcriptional machinery. However, examples of core promoter specificity have led to an alternate hypothesis in which specificity is achieved by core promoters with different sequence motifs that ...
Clarice KY Hong, Barak A Cohen
openaire   +2 more sources

Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement. [PDF]

, 2019
Eukaryotic DNA is packaged into nucleosome arrays, which are repositioned by chromatin remodeling complexes to control DNA accessibility. The Saccharomyces cerevisiae RSC (Remodeling the Structure of Chromatin) complex, a member of the SWI/SNF chromatin ...
Afonine, Afonine, Allen, Angus-Hill, Ashkenazy, Ashkenazy, Asturias, Badis, Buchan, Buchan, Cairns, Cairns, Campsteijn, Chaban, Chambers, Chatterjee, Clapier, Clapier, Côté, Da, Dechassa, Duan, Dutta, Dürr, El-Gebali, Emsley, Erkina, Filippakopoulos, Goddard, Han, Jones, Jones, Kadoch, Kasten, Klein-Brill, Krietenstein, Kuryan, Leschziner, Leschziner, Li, Liu, Lopéz-Blanco, Mashtalir, Morin, Nagai, Nakane, Ng, Patel, Pettersen, Puig, Saha, Sammak, Schorb, Schubert, Sen, Shim, Sievers, Skiniotis, Smith, Suloway, Söding, Tan, Tsunaka, Ungar, Valencia, Wagner, Wang, Wilson, Xia, Yan, Yang, Ye, Yen, Zhang, Zhang, Zhang, Zheng, Zivanov, Zivanov, Zukin   +79 more
core   +3 more sources

Fast Evolution of Core Promoters in Primate Genomes [PDF]

Molecular Biology and Evolution, 2008
Despite much interest in regulatory evolution, how promoters have evolved remains poorly studied, mainly owing to paucity of data on promoter regions. Using a new set of high-quality experimentally determined core promoters of the human genome, we conducted a comparative analysis of 2,492 human and rhesus macaque promoters and their neighboring nearly ...
Han, Liang, Yeong-Shin, Lin, Wen-Hsiung, Li   +2 more
openaire   +2 more sources

Genomic comparison of diverse Salmonella serovars isolated from swine. [PDF]

, 2019
Food animals act as a reservoir for many foodborne pathogens. Salmonella enterica is one of the leading pathogens that cause food borne illness in a broad host range including animals and humans.
Barrett, John B, Frye, Jonathan G, Gupta, Sushim K, Hiott, Lari M, Humayoun, Shaheen B, Jackson, Charlene R, McClelland, Michael, McMillan, Elizabeth A, Sharma, Poonam, Woodley, Tiffanie   +9 more
core   +2 more sources

Comparative genomics of Drosophila and human core promoters [PDF]

Genome Biology, 2006
Abstract Background The core promoter region plays a critical role in the regulation of eukaryotic gene expression. We have determined the non-random distribution of DNA sequences relative to the transcriptional start site in Drosophila melanogaster promoters to identify sequences that may be biologically
FitzGerald, Peter C, Sturgill, David, Shyakhtenko, Andrey, Oliver, Brian, Vinson, Charles   +4 more
openaire   +2 more sources

Phytochemicals: Extraction, Isolation, and Identification of Bioactive Compounds from Plant Extracts

Plants, 2017
There are concerns about using synthetic phenolic antioxidants such as butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA) as food additives because of the reported negative effects on human health.
Ammar Altemimi, Naoufal Lakhssassi, Azam Baharlouei, Dennis G. Watson, David A. Lightfoot   +4 more
doaj   +1 more source

Pan-Genome of Novel Pantoea stewartii subsp. indologenes Reveals Genes Involved in Onion Pathogenicity and Evidence of Lateral Gene Transfer

Microorganisms, 2021
Pantoea stewartii subsp. indologenes (Psi) is a causative agent of leafspot on foxtail millet and pearl millet; however, novel strains were recently identified that are pathogenic on onions. Our recent host range evaluation study identified two pathovars;
Gaurav Agarwal, Ronald D. Gitaitis, Bhabesh Dutta   +2 more
doaj   +1 more source

Finished Genome of the Fungal Wheat Pathogen Mycosphaerella graminicola Reveals Dispensome Structure, Chromosome Plasticity, and Stealth Pathogenesis [PDF]

, 2011
The plant-pathogenic fungus Mycosphaerella graminicola (asexual stage: Septoria tritici) causes septoria tritici blotch, a disease that greatly reduces the yield and quality of wheat.
Aerts, A., Antoniw, J., Bailey, A., Bluhm, B., Bowler, J., Bristow, J., Burgt, A., van der, Canto-Canché, B., Churchill, A.C.L., Conde-Ferràez, L., Cools, H.J., Coutinho, P.M., Crane, C.F., Csukai, M., Dehal, P., Dhillon, B., Donzelli, B., Foster, A.J., Geest, H.C., van de, Goodwin, S.B., Grigoriev, I.V., Grimwood, J., Ham, R.C.H.J., van, Hammond-Kosack, K.E., Hane, J.K., Henrissat, B., Kema, G.H.J., Kilian, A., Kobayashi, A.K., Koopmann, E., Kourmpetis, Y., Kuzniar, A., Lee, T.A.J., van der, Lindquist, E., Lombard, V., M'Barek, S., Ben, Maliepaard, C.A., Martins, N., Mehrabi, A., Nap, J.P.H., Oliver, R.P., Ponomarenko, A., Rudd, J.J., Salamov, A., Schmutz, J., Schouten, H.J., Shapiro, H., Stergiopoulos, I., Torriani, S.F.F., Tu, H., Vries, R.P., de, Waalwijk, C., Ware, S.B., Wiebenga, A., Wit, P.J.G.M., de, Wittenberg, A.H.J., Zwiers, L.H.   +56 more
core   +5 more sources

The Metalloprotease, Mpr1, Engages AnnexinA2 to Promote the Transcytosis of Fungal Cells across the Blood-Brain Barrier

Frontiers in Cellular and Infection Microbiology, 2017
Eukaryotic pathogens display multiple mechanisms for breaching the blood-brain barrier (BBB) and invading the central nervous system (CNS). Of the fungal spp., that cause disease in mammals, only some cross brain microvascular endothelial cells which ...
Sarisa Na Pombejra, Michelle Salemi, Brett S. Phinney, Angie Gelli   +3 more
doaj   +1 more source