Results 101 to 110 of about 898,016 (304)
Multi-mode Alfv\'enic Fast Particle Transport and Losses: Numerical vs. Experimental Observation
, 2013 In many discharges at ASDEX Upgrade fast particle losses can be observed due to Alfv\'enic gap modes, Reversed Shear Alfv\'en Eigenmodes or core-localized Beta Alfv\'en Eigenmodes.
Bilato, Roberto +6 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Reducing the Core Losses of Fe-Si-B Amorphous Alloy Ribbons by High Cooling Rate Planar Flow Casting. [PDF]
Materials (Basel), 2022 Li D, Wang W, Liu T, Li L, Lu Z.
europepmc +1 more source
Hotspots, mantle plumes and core heat loss [PDF]
Earth and Planetary Science Letters, 2002 Abstract The heat flux at the core–mantle boundary (CMB) is a key parameter for core dynamics since it controls its cooling. However, it is poorly known and estimates range from 2 TW to 10 TW. The lowest bound comes from estimates of buoyancy fluxes of hotspots under two assumptions: that they are surface expression of mantle plumes originating from ...
openaire +2 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
IEEE Open Journal of Power ElectronicsThis paper extends the Generalized Steinmetz Equation (GSE) to account for the influence of mechanical stress on ferrite core losses. Experimental measurements are used to quantify the effects of compressive and tensile stresses on the relative ...
Jannik Schafer +2 more
doaj +1 more source
Deconvolution of core electron energy loss spectra
Ultramicroscopy, 2009 Different deconvolution methods for removing multiple scattering and instrumental broadening from core loss electron energy loss spectra are compared with special attention to the artefacts they introduce. The Gaussian modifier method, Wiener filter, maximum entropy, and model based methods are described.
Verbeeck J., Bertoni G.
openaire +4 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source