Results 111 to 120 of about 893,570 (306)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Core losses of a permanent magnet synchronous motor with an amorphous stator core under inverter and sinusoidal excitations

AIP Advances, 2018
We report core loss properties of permanent magnet synchronous motors (PMSM) with amorphous magnetic materials (AMM) core under inverter and sinusoidal excitations. To discuss the core loss properties of AMM core, a comparison with non-oriented (NO) core
Atsushi Yao, Takaya Sugimoto, Shunya Odawara, Keisuke Fujisaki   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The response of a high voltage transformer with various geometries of core joint design [PDF]

, 2017
The core losses in a three phase transformer can be significantly reduced by improving the core joint geometry. The researchers were applied numerous types of T-joint designs in order to reach the optimum design that can be used in three phase ...
Ab Kadir, Mohd Zainal Abidin, Alyozbaky, Omar Sh., Izadi, Mahdi, Mohd Isa, Maryam   +3 more
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Bacterial wilt resistance in tomato, eggplant and pepper : genetic resources challenged with the multifaceted Ralstonia solanacearum species complex : [P3-49] [PDF]

, 2010
Bacterial wilt caused by strains belonging to the #Ralstonia solanacearum# species complex inflicts severe economic losses in many crops worldwide. Host resistance remains the most effective control strategy against the bacterial wilt.
Chiroleu, Frédéric, Daunay, Marie-Christine, Dintinger, Jacques, Frary, Anne, Lebeau, Aurore, Palloix, Alain, Prior, Philippe, Wang, Jaw-Fen, Wicker, Emmanuel   +8 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Application of advanced materials to rotating machines [PDF]

, 1983
In discussing the application of advanced materials to rotating machinery, the following topics are covered: the torque speed characteristics of ac and dc machines, motor and transformer losses, the factors affecting core loss in motors, advanced ...
Triner, J. E.
core   +1 more source

Microstructure, soft magnetic properties and applications of amorphous Fe-Co-Si-B-Mo-P alloy

AIP Advances, 2018
DC thermomagnetic properties of Fe51Co12Si16B8Mo5P8 amorphous alloy in the as-quenched and after annealing below crystallization temperature are investigated.
Mariusz Hasiak, Marcel Miglierini, Mirosław Łukiewski, Amadeusz Łaszcz, Marek Bujdoš   +4 more
doaj   +1 more source