Results 51 to 60 of about 891,437 (305)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Three-Dimensional Numerical Field Analysis in Transformers to Identify Losses in Tape Wound Cores
To find the total core losses in 1-phase medium-frequency transformers, a 3D numerical field analysis was carried out. The proposed numerical modeling was based on the extended iterative homogenization method (IHM) developed by the authors.
Dariusz Koteras, Bronislaw Tomczuk
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Induction motors are a significant consumer of electricity. One of the crucial elements of losses in an induction motor is core losses. Core losses become dominant in motors powered by an inverter at higher frequencies.
Maria Dems, Krzysztof Komeza
doaj +1 more source
Modeling Frequency-Dependent Losses in Ferrite Cores [PDF]
We suggest a practical approach for modeling frequency-dependent losses in ferrite cores for circuit simulation. Previous work has concentrated on the effect of eddy-current losses on the shape of the B--H loop, but in this paper we look at the problem from the perspective of energy loss and propose a different network for accurately modeling power ...
Wilson, Peter R. +2 more
openaire +2 more sources
Nonlinear alfv\'enic fast particle transport and losses [PDF]
Magnetohydrodynamic instabilities like Toroidal Alfv\'en Eigenmodes or core-localized modes such as Beta Induced Alfv\'en Eigenmodes and Reversed Shear Alfv\'en Eigenmodes driven by fast particles can lead to significant redistribution and losses in ...
Brüdgam, Michael +4 more
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Impact of Core Sheet Cutting Method on Parameters of Induction Motors
The method of cutting motor core sheets causes a change in their magnetic properties and core losses, especially additional losses. Reducing motor losses is very important because of the fulfillment of increasingly stringent requirements set by ...
Maria Dems +3 more
doaj +1 more source
On the variation with flux and frequency of the core loss coefficients in electrical machines [PDF]
A model of core losses, in which the hysteresis coefficients are variable with the frequency and induction (flux density) and the eddy-current and excess loss coefficients are variable only with the induction, is proposed. A procedure for identifying the
Dellinger, S.J. +5 more
core +1 more source

