Results 181 to 190 of about 4,460,645 (227)

Correction: K27-linked RORγt ubiquitination by Nedd4 potentiates Th17-mediated autoimmunity

Journal of Biomedical Science
Qiuming Zeng, Hui Guo, Na Tang, Pranav S. Renavikar, Nitin J. Karandikar, Amy E. Lovett-Racke, Michael K. Racke, Chengkai Yan, Rong Tang, Sushmita Sinha, Krishnendu Ghosh, Jeremy P. Ryal, Song Ouyang, Min Chen, Foued Amari, Coppola Vincenzo, R. Marshall Pope, Yalan Li, Huan Yang, Wallace Y. Langdon, Jian Zhang   +20 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

Comparative study between single core model and detail core model of CFD modelling on reactor core cooling behaviour

IOP Conference Series: Materials Science and Engineering, 2018
openaire   +1 more source

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A core model for G2

Involve, a Journal of Mathematics, 2021
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Cotton, Benjamin, Williams, Nathan F.
openaire   +2 more sources

Square in Core Models

Bulletin of Symbolic Logic, 2001
AbstractWe prove that in all Mitchell-Steel core models, □k holds for all k. (See Theorem 2.) From this we obtain new consistency strength lower bounds for the failure of □k if k is either singular and countably closed, weakly compact, or measurable. (Corollaries 5, 8, and 9.) Jensen introduced a large cardinal property that we call subcompactness; it ...
Ernest Schimmerling, Martin Zeman
openaire   +2 more sources

The CORE Diabetes Model

Current Medical Research and Opinion, 2004
(2004). The CORE Diabetes Model. Current Medical Research and Opinion: Vol. 20, No. sup1, pp. S1-S3.
Michael, Brändle, William H, Herman
openaire   +2 more sources

The core model

1982
The core model, K, is a generalization of Gödel's constructible universe of set theory; K is used to produce 'fine structural' results of a less restrictive kind. This book aims to introduce the core model to those with a basic knowledge of axiomatic set theory.
  +4 more sources