Results 31 to 40 of about 616,913 (244)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Decoupling and Aligning Modality-Shared Semantics for Single-Domain Generalization in Hyperspectral Image Classification

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Leveraging natural language to guide visual models for single-domain generalization (SDG) in hyperspectral image classification (HSIC) is a promising yet challenging frontier.
Xi Chen   +4 more
doaj   +1 more source

YOLO-DCTI: Small Object Detection in Remote Sensing Base on Contextual Transformer Enhancement

open access: yesRemote Sensing, 2023
Object detection for remote sensing is a fundamental task in image processing of remote sensing; as one of the core components, small or tiny object detection plays an important role.
Lingtong Min   +5 more
doaj   +1 more source

Efficient classification using parallel and scalable compressed model and Its application on intrusion detection

open access: yes, 2014
In order to achieve high efficiency of classification in intrusion detection, a compressed model is proposed in this paper which combines horizontal compression with vertical compression.
Chen, Tieming   +3 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

More than money: Core self-evaluations, job characteristics and work-family conflict among women

open access: yesHeliyon
Integrating work and family life is a relevant concern, especially for women in the banking industry. While the impact of job characteristics on work-family conflict is well-documented, the moderating role of core self-evaluations (CSE) remains ...
Lawrence Ejike Ugwu   +2 more
doaj   +1 more source

SurF: an innovative framework in biosecurity and animal health surveillance evaluation [PDF]

open access: yes, 2018
Surveillance for biosecurity hazards is being conducted by the New Zealand Competent Authority, the Ministry for Primary Industries (MPI) to support New Zealand's biosecurity system.
Bingham, P   +9 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Relocation and Livelihood Concerns of Sariska Tiger Project, Rajasthan: A Pride or Plight? [PDF]

open access: yesSpace and Culture, India, 2015
It is well known that Sariska Tiger Reserve is a home to the India’s national animal - the Bengal Tiger (Panthera tigris tigris). The crux of this research is to examine the role of local peoples in the conservation of Sariska Tiger project, which was ...
Muraree Lal Meena
doaj   +2 more sources

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