Results 41 to 50 of about 42,772 (260)
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
ABAC access control policy generation technique based on deep learning
To solve the problem of automatic generation of access control policies, an access control policy generation framework based on deep learning was proposed.Access control policy based on attributes could be generated from natural language texts.This ...
Aodi LIU, Xuehui DU, Na WANG, Rui QIAO
doaj +2 more sources
The Task of Detecting Unacceptable Information Security Events in the Information Infrastructure
The purpose of the study is to develop an advanced approach to solving the task of detecting unacceptable events in the field of information security to improve incident detection accuracy and reduce the number of false positives.
Darya A. Evdokimova, Andrey A. Mikryukov
doaj +1 more source
Model complex production business contains the attributes of completion time, accuracy, and so on; these factors influence each other; and pursuing the balance of these factors is the core idea of the article.
Zhi-yong Luo +3 more
doaj +1 more source
This study investigates the value of the contribution of HEIs’ context in developing graduates enterprise skills. HEIs are under pressure to develop more enterprising graduates, particularly with the increasing numbers of graduates seeking employment and
Refai, Deema +2 more
core +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Many secondary students learn to read academic texts in a non-native language. However, classroom guidance and diagnostic tests often rely on flat skills lists that ignore prerequisite relations among reading processes.
Muhamad Firdaus Mohd Noh +2 more
doaj +1 more source
Rationalization of the parameters of the cylindrical bridge support (theoretical basis)
Paper deals with a new constructive solution of a massive concrete pillar intended, mostly, for construction of railway and road bridge supports and with procedure of rationalization of its parameters.
Shmukler Valery +2 more
doaj +1 more source
Important non-academic attributes in Australian initial teacher education
Current policy initiatives are requiring Initial Teacher Education (ITE) providers to select teachers with both the academic and non-academic attributes that ensure their suitability for teaching and their classroom readiness.
Bianca Coleman (14734045) +2 more
core
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source

