Results 31 to 40 of about 42,258 (219)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Serial reduction optimization research of complex product workflow’s accuracy under the time constraint

open access: yesAdvances in Mechanical Engineering, 2016
Model complex production business contains the attributes of completion time, accuracy, and so on; these factors influence each other; and pursuing the balance of these factors is the core idea of the article.
Zhi-yong Luo   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Task of Detecting Unacceptable Information Security Events in the Information Infrastructure

open access: yesОткрытое образование (Москва)
The purpose of the study is to develop an advanced approach to solving the task of detecting unacceptable events in the field of information security to improve incident detection accuracy and reduce the number of false positives.
Darya A. Evdokimova, Andrey A. Mikryukov
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

ABAC access control policy generation technique based on deep learning

open access: yesTongxin xuebao, 2020
To solve the problem of automatic generation of access control policies, an access control policy generation framework based on deep learning was proposed.Access control policy based on attributes could be generated from natural language texts.This ...
Aodi LIU, Xuehui DU, Na WANG, Rui QIAO
doaj   +2 more sources

Developing a hierarchical cognitive second language (L2) reading model using multi-dimensional fuzzy Delphi method and interpretive structural modeling

open access: yesActa Psychologica
Many secondary students learn to read academic texts in a non-native language. However, classroom guidance and diagnostic tests often rely on flat skills lists that ignore prerequisite relations among reading processes.
Muhamad Firdaus Mohd Noh   +2 more
doaj   +1 more source

Rationalization of the parameters of the cylindrical bridge support (theoretical basis)

open access: yesMATEC Web of Conferences, 2018
Paper deals with a new constructive solution of a massive concrete pillar intended, mostly, for construction of railway and road bridge supports and with procedure of rationalization of its parameters.
Shmukler Valery   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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