Results 51 to 60 of about 42,772 (260)

Development of a tool for quality control audits in hospital enteral nutrition

Nutrición Hospitalaria, 2014
Background and aims: Malnutrition is very prevalent in hospitals, causing physical capacity deterioration, increasing complications and raising mortality. This scenario overloads public health costs enormously.
Guilherme Duprat Ceniccola, Wilma Maria Coelho Araújo, Rita Akutsu   +2 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Interactive Environment-Aware Planning System and Dialogue for Social Robots in Early Childhood Education

Applied Sciences
In this study, we propose an interactive environment-aware dialog and planning system for social robots in early childhood education, aimed at supporting the learning and social interaction of young children.
Jiyoun Moon, Seung Min Song
doaj   +1 more source

The use of conceptual components in language production: an ERP study

Frontiers in Psychology, 2014
According to frame-theory, concepts can be represented as structured frames that contain conceptual attributes (e.g., ‘color’) and their values (e.g., ‘red’).
Alexandra eRedmann, Alexandra eRedmann, Ian eFitzPatrick, Ian eFitzPatrick, Frauke eHellwig, Frauke eHellwig, Peter eIndefrey, Peter eIndefrey   +7 more
doaj   +1 more source

Surface soil metal elements variability affected by environmental and soil properties.

PLoS ONE, 2021
Identifying the factors controlling the spatial variability of soil metal elements could be a challenge task due to the interaction of environmental attributes and human activities.
Wei Wu, Yu Li, Mingshu Yan, Lechao Yang, Jiali Lei, Hong-Bin Liu   +5 more
doaj   +1 more source

Quality of service for workflows and web service processes

, 2004
Workflow management systems (WfMSs) have been used to support various types of business processes for more than a decade now. In workflows for e-commerce and Web service applications, suppliers and customers define a binding agreement or contract between
Cardoso, Jorge, Sheth, Amit P., Krys Kochut, Kochut, Krzysztof J., John Miller, Jonathan Arnold, Jorge Cardoso, Arnold, Jonathan, Miller, John A., Amit Sheth   +9 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

“There are risks to be taken and some just push it too far”: how farmers perceive quad‐bike incident risk

Australian and New Zealand Journal of Public Health, 2016
Objective: To qualitatively explore how farmers perceive personal risk of an occupational quad‐bike incident and develop a model of the factors that modify this perception. Methods: Grounded theory methods were used to inform data collection and analysis.
Lynne Clay, Jean Hay‐Smith, Gareth Treharne, Stephan Milosavljevic   +3 more
doaj   +1 more source

A Concept Analysis of Systems Thinking

, 2016
PURPOSE This concept analysis, written by the National Quality and Safety Education for Nurses (QSEN) RN-BSN Task Force, defines systems thinking in relation to healthcare delivery.
Merriam, Deborah, Wiggs, Carol M., Winegardner, Sherri, Ruggiero, Jeanne, Dolansky, Mary A., Wiggs, Carol, Dolansky, Mary, Phillips, Janet, Goldschmidt, Karen A., Phillips, Janet M., Scardaville, Debra, Stalter, Ann, Scardaville, Debra L., Ruggiero, Jeanne S., Stalter, Ann M., Goldschmidt, Karen   +15 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source