Results 71 to 80 of about 616,913 (244)

An algorithm evaluation for discovering classification rules with gene expression programming

open access: yesInternational Journal of Computational Intelligence Systems, 2016
In recent years, evolutionary algorithms have been used for classification tasks. However, only a limited number of comparisons exist between classification genetic rule-based systems and gene expression programming rule-based systems.
Alain Guerrero-Enamorado   +3 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Reframing Professionalism: The Virtuous Professional

open access: yesMedEdPublish, 2018
In response to prevalent unprofessional behaviors during the 1990s, the medical school administration at Michigan State University's College of Human Medicine developed a student curriculum for professional development, called "The Virtuous Student ...
William Wadland   +7 more
doaj  

Quality analysis of critical control points within the whole food chain and their impact on food quality, safety and health (QACCP) [PDF]

open access: yes, 2010
The overall objective of the project was to optimise organic production and processing in order to improve food quality and increase health promoting aspects in consumer products.
Kahl, Johannes   +6 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

A Task-Based Approach to Organization: Knowledge, Communication and Structure [PDF]

open access: yes
We bridge a gap between organizational economics and strategy research by developing a task-based approach to analyze organizational knowledge, process and structure, and deriving testable implications for the relation between production and ...
Luis Garicano, Yanhui Wu
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

A Metadata-Enabled Scientific Discourse Platform [PDF]

open access: yes, 2010
Scientific papers and scientific conferences are still, despite the emergence of several new dissemination technologies, the de-facto standard in which scientific knowledge is consumed and discussed.
Chenu-Abente, Ronald   +3 more
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

A multi-stage hybrid framework for anomaly detection in attributed graphs using attention-driven representation and community-aware scoring

open access: yesDiscover Applied Sciences
Detecting anomalies in attributed graphs is a crucial yet challenging task due to the interplay between node attributes, graph structure, and contextual dependencies.
Wasim Khan   +5 more
doaj   +1 more source

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