Results 291 to 300 of about 1,245,934 (342)

Biomimetic Scaffolds with Dual Gradients of Biological Effectors for Tendon‐to‐Bone Repair

open access: yesAdvanced Healthcare Materials, EarlyView.
The authors have developed a biomimetic scaffold with dual gradients through a diffusion‐driven method. The scaffold features funnel‐shaped microchannels for cell infiltration, while the dual gradients synergetically induce the graded differentiation of mesenchymal stem cells into osteoblasts, chondrocytes, and tenocytes, allowing for a seamless ...
Min Hao   +3 more
wiley   +1 more source

Development of a Modular Ribonucleoprotein Complex as a General Strategy to Deliver RNAi Therapeutics

open access: yesAdvanced Healthcare Materials, EarlyView.
A modular and customizable RNAi therapeutics delivery platform composed of a pseudosymmetric human RNA binding protein‐siRNA complex (SmiRNP) is developed. By fusing a targeting module and an endosomal escape peptide onto the delivery platform, SmiRNP successfully delivered siRNA to silence the KRAS oncogene in a colorectal carcinoma cell line, leading
Nok Yin Tam   +9 more
wiley   +1 more source

Determination of Aflatoxins B1, B2, G1, and G2 concentrations in cheese puffs made from corn flour in Iran. [PDF]

open access: yesSci Rep
Reshadi S   +8 more
europepmc   +1 more source

Upconversion Nanoparticle‐Covalent Organic Framework Core–shell Particles as Therapeutic Microrobots Trackable With Optoacoustic Imaging

open access: yesAdvanced Materials, EarlyView.
Upconversion nanoparticle‐covalent organic framework core–shell particles provide enhanced contrast for optoacoustic imaging by leveraging the optical absorption of upconversion luminescence within the covalent organic framework matrix. Beyond their role as contrast agents, these particles enable customizable therapeutic agent loading and release, as ...
Dong Wook Kim   +8 more
wiley   +1 more source

Soil erosion and lateral carbon fluxes from corn stover-derived biofuel. [PDF]

open access: yesSci Rep
Zhang X   +7 more
europepmc   +1 more source

Selective Lipolysis by Photoactivation of Chaperone‐Mediated Autophagy Using Adipocyte Membrane‐Coated Nanoparticle in Hydrogel

open access: yesAdvanced Materials, EarlyView.
Adipocyte membrane‐coated nanoparticles loaded with rosiglitazone in hydrogel offer an alternative approach to conventional obesity treatments. This system selectively targets adipocytes, inducing lipolysis by activating chaperone‐mediated autophagy through mild photothermal stimulation.
Jaehyun Choi   +8 more
wiley   +1 more source

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